Why do you think that high levels of leptin, a circulating hormone that is produced by fat cells and plays a role in body metabolism and obesity, in obese individuals are insufficient to curb their appetite

Answers

Answer 1

High levels of leptin in obese individuals are insufficient to curb their appetite due to a phenomenon called leptin resistance. This means that despite elevated levels of leptin, the brain, and body do not respond appropriately to its signals, leading to a lack of appetite control.

Leptin is a hormone produced by fat cells that plays a crucial role in regulating body metabolism and appetite. When fat cells release leptin into the bloodstream, it acts on the hypothalamus in the brain, signaling feelings of fullness and reducing appetite. In non-obese individuals, this system works effectively to maintain energy balance.

However, in obese individuals, a condition known as leptin resistance occurs. Leptin resistance means that the brain and body become less responsive to the signals of leptin, leading to a diminished ability to regulate appetite and energy balance. As a result, even with high levels of circulating leptin, obese individuals do not experience the normal suppression of appetite.

The exact mechanisms behind leptin resistance are still being studied, but it is believed to involve a combination of genetic, environmental, and hormonal factors. Some potential factors contributing to leptin resistance include chronic inflammation, impaired leptin transport across the blood-brain barrier, dysregulation of leptin receptors, and disturbances in the signaling pathways involved in appetite regulation.

Leptin resistance creates a situation where the body's natural feedback loop for appetite control is disrupted. As a consequence, obese individuals may continue to experience heightened appetite and struggle to regulate their food intake, despite having elevated levels of leptin. Addressing leptin resistance and restoring sensitivity to leptin signals may be an important aspect of managing obesity and developing effective interventions.

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Related Questions

define evolution as clearly and completely as you can

Answers

Evolution is how we came to be as human beings ranging from rats, apes etc. This has helped us increase our survival skills and communication (ever since the beginning)

Describe characteristics for the cellular processes of exocytosis and endocytosis

Answers

Endocytosis and Exocytosis are the processes of transport through the plasma membrane. These are responsible for the transport of solute particles in and out of the cell.

What is Cellular Transport?

The transport of materials or substances across the cell membrane is called cellular transport. Endocytosis is the process of capturing a substance from outside environment of the cell by engulfing it within the plasma membrane, and bringing it into the cell.

However, Exocytosis describes the process of vesicles fusion with the plasma membrane and release of the contents outside of the cell.

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to support the symbiotic hypothesis presented in the passage, mitochondria should be similar to bacteria in which of the following ways?

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To support the symbiotic hypothesis presented in the passage, mitochondria should be similar to bacteria in possessing their own DNA

Option (A) is correct.

The symbiotic hypothesis proposes that mitochondria originated from a symbiotic relationship between an ancestral eukaryotic cell and a free-living bacterium. To support this hypothesis, mitochondria should exhibit similarities to bacteria.

One of the key similarities is the possession of their own DNA. Bacteria have their own distinct genetic material in the form of DNA, and mitochondria also possess their own DNA, known as mitochondrial DNA (mtDNA).

This similarity in DNA structure and function suggests a shared evolutionary origin between mitochondria and bacteria. Therefore, option A, "Possessing their own DNA," is the correct choice to support the symbiotic hypothesis.

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The complete question:

To support the symbiotic hypothesis presented in the passage, mitochondria should be similar to bacteria in which of the following ways?

A) Possessing their own DNA

B) Reproducing by binary fission

C) Having a cell wall

D) Engaging in photosynthesis

Recycling of solid waste minimizes pollution. Give reason.

Answers

Recycling prevents the emissions of many greenhouse gases and water pollutants, and saves energy. Using recovered material generates less solid waste. Also, when products are made using recovered rather than virgin materials, less energy is used during manufacturing, and fewer pollutants are emitted.

Indicate if the conditions described would result in the development of a male or a female individual. SRY is a gene on the Y involved in initiating development of the male phenotype in humans. -An individual with only one X chromosome and a Y chromosome with an SRY gene mutation -One X chromosome and a Y chromosome with the SRY gene deleted -One each of the X and Y chromosome -Only one X chromosome -One normal X chromosome and an X chromosome with an SRY gene insertion -Two X chromosomes and a Y chromosome -Four X chromosomes and a Y chromosome

Answers

The correct option for the condition that results in the development of a male or a female individual is all of the above.

What is the SRY gene?

SRY gene is the gene that is responsible for the instructions making a protein called the sex-determining region y protein. This gene is responsible for the development of the testis.

One X chromosome and a Y chromosome with the SRY gene deleted = female

One normal X chromosome and an X chromosome with an SRY gene insertion = male

Two X chromosomes and a Y chromosome = male

An individual with only one X chromosome and a Y chromosome with an SRY gene mutation = male

Four X chromosomes and a Y chromosome = male

One each of the X and Y chromosomes = male

Thus for the above question, all the options are suitable.

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what is the genotype of a heterozygous axial plant

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The genotypic ratio of the above cross will be 1:2:1, that is 1 homologous plant with axial flowers (AA), 2 heterozygous plants with axial flowers (Aa) and 1 homologous plant with terminal flower (aa).

Compare the two ways in which earth was supplied with enough water to have an ocean. Which is likely to have contributed most of the water on Earth?

Answers

Answer:

One possible way is that the Earth held onto some water when it formed, as there would have been ice in the nebula of gas and dust (called the proto-solar nebula) that eventually formed the sun and the planets about 4.5 billion years ago. Another possible way is that some of that water has remained with the Earth, and might be recycled through the planet's mantle layer. I believe the proto-solar nebula is the most reasonable way since the features of all planets are brought by the elements that formed them; in this case, it was the nebula of gas and dust.

Explanation:

Hopefully this helped! :)

some microbes can produce the enzyme dnase, which is secreted outside of the cell and breaks down nucleic acids in the microbe’s environment. dnase is an example of a _____________________ .

Answers

DNase is an example of an exoenzyme. Microbes can produce the enzyme DNase which is secreted outside of the cell

Exoenzymes are enzymes that are secreted by cells and function outside of the cell. These enzymes are important for the breakdown of large molecules, such as nucleic acids, into smaller molecules that can be easily absorbed by the cell. In the case of DNase, the enzyme breaks down nucleic acids into smaller nucleotides, which can then be taken up by the microbe and used for energy or as building blocks for the synthesis of new nucleic acids.

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photosynthesis and cellular respiration?

Answers

Answer:Photosynthesis converts carbon dioxide and water into oxygen and glucose. Glucose is used as food by the plant and oxygen is a by-product. Cellular respiration converts oxygen and glucose into water and carbon dioxide. Water and carbon dioxide are by- products and ATP is energy that is transformed from the process.

Explanation:

Which of the following choices
correctly shows the way energy
flows in an ecosystem?
A. Seaweed to Fish to Seal to Polar
Bear to Bacteria
B. Polar Bear to Seal to Fish to
Seaweed to Bacteria
C. Bacteria to Seaweed to Fish to Seal
to Polar Bear
D. Seaweed to Bacteria to Seal to Fish
to Polar Bear

Answers

Answer:

C. Bacteria to Seaweed to Fish to Seal to Polar Bear

Explanation:

Every ecosystem consists of multiple organisms. These organisms feed on each other, forming a food chain. The energy within an ecosystem flows through the food chain.

Here, we're supposed to determine which food chain is the correct one. All organisms can be divided into producers and consumers. Producers are organisms that produce their own food, while consumers feed by consuming other organisms.

The only food chain that makes sense is shown in option C. I wouldn't say that bacteria belong to it as the seaweed is an example of a producer. It doesn't consume other organisms. But, fish feed on it, then seals eat the fish, and polar bears eat the seals. This is why we can safely say that option C is the correct one, despite bacteria being present there. Any other combination wouldn't work as, for example, bacteria (A) and seals (B) can't eat polar bears and the fish can't eat seals (D).

help me if you can please and ty

help me if you can please and ty

Answers

i do believe the second answer is the right one

PLS HELP ASAP
Which of the following is a renewable energy source?
A) sun
B) water
C) wind
D) biomass
E) all of the above

Answers

E. All of the above.
answer E

explanation :

Loni makes a diagram to help organize what she has learned about the gas laws.


Which label belongs in the region marked X?

involves changes in temperature
has a constant volume
shows an inversely proportional relationship
does not describe pressure changes

Answers

Answer:

Shows an inversely proportional relationship.

Explanation:

The Boyle's law belongs in the region marked X whereas the other circle belongs to Charles law. There is inverse relationship between the two circles or these two laws because in Boyle's law, temperature is constant while on the other hand, in Charles law pressure is constant instead of temperature. In Boyle's law, pressure of a gas is inversely with its volume whereas in Charles law, the volume of a gas is directly proportional to its absolute (Kelvin) temperature.

Steps of the scientific method. I don’t understand!!!

Steps of the scientific method. I dont understand!!!

Answers

1. research question
2. background research
3. hypothesis
4. controlled experiment
5. data analysis
6. data collection
7. conclusion

What is the concentration of carbon dioxide in this sample

Answers

Answer:

38.2 mmita. 6. Draw conclusions: Between the right ventricle and the left atrium,

Explanation:

what is a characteristic of monoclonal antibodies? question 2 options: they are produced by a single antibody-producing cell and are specific for different epitopes of antigen. they are produced by different antibody-producing cells and are specific for one epitope of antigen. they are produced by a single antibody-producing cell and are specific for one epitope of antigen. they are produced by different antibody-producing cells and are specific for different epitopes of antigen. they are precursors of polyclonal antibodies.

Answers

Monoclonal antibodies are produced by a single antibody-producing cell and are specific for one epitope of an antigen. Option 2 is the right choice.

An antibody that is formed from a cell lineage that was made by cloning a specific white blood cell is referred to as a monoclonal antibody (mAb) or more infrequently as a moAb. Every successive antibody that was produced in this manner may be traced back to a single parent cell.

Monoclonal antibodies have the potential to have monovalent affinity, meaning that they can only bind to a single epitope (the part of an antigen that is recognized by the antibody). Polyclonal antibodies, on the other hand, are able to bind to more than one epitope, and they are typically produced by several distinct plasma cell lineages that secrete antibodies. The therapeutic targets of a single monoclonal antibody can be expanded to include two epitopes when the process of engineering bispecific monoclonal antibodies is carried out.

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during respiration, what is breathed in and what is breathed out?

Answers

Answer:

When you inhale (breathe in), air enters your lungs, and oxygen from that air moves to your blood. At the same time, carbon dioxide, a waste gas, moves from your blood to the lungs and is exhaled (breathed out)

Explanation:

Answer:

carbon dioxide, a waste gas, moves from your blood to the lungs and is exhaled (breathed out).

Explanation:

I literally just had this one in school

To fill out the chart on nonrenewable and renewable natural resources, should Hector add trees under the heading "Renewable
Resources"?

A)
No. Trees can die from disease.
B)
Yes. There are many uses for trees.
C)
Yes. Trees can be cut down but planted again.
D)
No. There is only so much land for trees to grow.

To fill out the chart on nonrenewable and renewable natural resources, should Hector add trees under

Answers

Answer:

c

Explanation:

the market for wood furniture and other products are on high demand so cutting down and planting again will help in availability and good weather

the small circular molecules of dna commonly found in bacteria are called _______

Answers

The small circular molecules of DNA commonly found in bacteria are called "plasmids."

What are plasmids?

Plasmids are separate from the main bacterial chromosome and can be transferred between bacteria. Restriction enzymes are proteins that can cut DNA at specific sequences, and they are often used in molecular biology to manipulate plasmids for various purposes, such as cloning or gene editing.

Role of plasmids:

The small circular molecules of DNA commonly found in bacteria are called plasmids. These plasmids can be cut by restriction enzymes, which are enzymes that recognize specific DNA sequences and cut the DNA at those sites. This ability to manipulate plasmids with restriction enzymes has made them an important tool in genetic engineering and biotechnology.

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All of the following are considered protists except

amoeba , plasmodium , mushroom , or seaweed

Answers

all are protists except seaweed because mushroom are fungi which are considered protists

Which is required for sexual reproduction?
mitosis
binary fission
diploid cell production
meiosis

Answers

Answer:

diploid cell production

Explanation:

in humans

Please answer the question in the photo! (will mark Brainliest if correct)

Please answer the question in the photo! (will mark Brainliest if correct)

Answers

Option 4 is correct - your kidney controls the water level through nephron tubes whenever you have low amounts of water that have been detected in your blood.

Because of drinking less water in a day, we experienced faintness and weak which led to the condition of dehydration. In this situation, saving a single drop of water becomes crucial for our body to survive.

Here, the Kidney plays the role of hero and controls the water level of the body using the hormone ADH (Antidiuretic hormone) released by the Pituitary gland.In a time of dehydration, the kidney starts absorbing more water into the nephron tubes which resulted in less urine production.After the detection of the low amount of water, these signaled enzymes, pump salts into nephron tubes because of the presence of more salt than usual which need to be balanced out by water.

Therefore, Option 4 is correct.

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Hello! I have to write an essay based on the Water Cycle and what it is/does. I will give Brainliest for the correct answer. I will also give 20 points to whoever writes the essay, and has the correct answer. Good luck.

Answers

Answer: The water cycle also known as the hydrolic cycle describes the always foward rotation above and below the surfaces of the earth. The mass of water on earths surface remains fairly consistant. However, the water splits up into diffrent groups, freshwater, saline water, ice, and atmospheric water. The water can travel between catorgories such as river to ocean or ocean to atmosphere through evaporation, condensation, precipatation, surface runoff and subsurface flow. When water go through these physical process it can change aswell such as being a liquid, solid,and gas. During evaporation it takes water from it surroundings and cools its enviromwnt,

the exchanges in heat fluctuate the climates tempature.

What is the difference between a eukaryote and a prokaryote in terms of what they have within in them?

Answers

Answer:

The primary distinction between these two types of organisms is that eukaryotic cells have a membrane-bound nucleus and prokaryotic cells do not. ... The nucleus is only one of many membrane-bound organelles in eukaryotes. Prokaryotes, on the other hand, have no membrane-bound organelles.

Which of the following statements is/are correct concerning biodiversity?

Biodiversity has a spiritual value


The conservation of biodiversity is crucial to protect our health


Food biodiversity is the central component of quality diet and food safety


Global anthropogenic change is the cause of the unprecedented loss of biodiversity in the planet


Biodiversity refers to diversity of life in all its forms, from the molecular level to the ecosystem level

Answers

The statement which are correct regarding biodiversity are the conservation of biodiversity is crucial to protect our health and Global anthropogenic change is the cause of the unprecedented loss of biodiversity in the planet.Thus, option B and D are correct.

Who contributes to maintain the balance of nature?

Every species on the Earth contributes significantly to the nature's intricate balancing act. Forests are the fragmented as the result of the natural disturbances just like fires or changes in land use like building roads.

As the result of these habitat alterations, biodiversity has significantly impacted since limited habitat fragments can only maintain weak populations that are more susceptible to extinction.

Therefore, The statement which are correct regarding biodiversity are the conservation of biodiversity is crucial to protect our health and Global anthropogenic change is the cause of the unprecedented loss of biodiversity in the planet.Thus, option B and D are correct.

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Rex rabbits have short fur and Angora rabbits have long fur. When mated together these rabbits produce offspring with medium length fur.


On a sheet of paper, make a Punnett square showing a cross that could result in the birth of short fur, long fur and medium fur babies.




What would be the parent genotypes that could result in short fur, long fur, and medium fur babies?

Answers

The offspring of an Angora and Rex rabbit hybrid have fur that is significantly longer than that of a Rex rabbit. There is a 0.25 percent probability that the child will have long fur based on the genotype of the parents.

The length of the offspring's' fur indicates an imperfect dominant inheritance pattern. Incomplete dominance is an inheritance pattern in which the phenotype of the offspring closely matches that of one parent more than the other, but is intermediate between the phenotypes of the parents.

In this instance, the progeny have fur length that is roughly equivalent to that of an Angora rabbit but slightly longer than that of a Rex rabbit. This is an illustration of partial dominance.

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In your own words, explain the process of translating mrna into a polypeptide sequence (protein). Us the terms: mrna, amino acid, polypeptide, ribosome, trna, and codon.

Answers

The biological procedure by which a polypeptide is created from an mRNA molecule is known as mRNA translation.

What is mRNA ?

In molecular biology, messenger ribonucleic acid is a single-stranded RNA molecule that is read by a ribosome during the protein-synthesis process and corresponds to the genetic sequence of a gene.

The function of mRNA is to transport protein information from DNA in a cell's nucleus to the cytoplasm, or watery interior, where the machinery responsible for making proteins reads the mRNA sequence and converts each three-base codon into an amino acid that belongs in a protein chain that is expanding.

The cytoplasm receives a "message" from the nucleus via mRNA. The nucleotide sequence of the mRNA, which functioned as a template for the mRNA's synthesis, is complementary to the nucleotide sequence of the DNA and contains the message. Translation is the process of creating proteins from mRNA.

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The drawing below was sketched by a student who was observing cells under a microscope.




In what kingdom does the above cell likely belong?

The drawing below was sketched by a student who was observing cells under a microscope.In what kingdom

Answers

Answer:

protista

Explanation:

It just looks like a protista cell, I think

how many living things are there on the plant?

Answers

Answer:

8.7 million species of plants and animals are in existence at the moment. Moire are being discovered everyday (at least I think so cx)

Explanation:

Hope this helped-

In a sample population of people 36% have recessive trait of "free" earlobe (q2). What is the frequency of the dominant allele for attached earlobes, p?

Answers

Answer:

The frequency of the dominant allele for attached earlobes, p = 0.4

Explanation:

Due to technical problems, you will find the complete explanation in the attached files.

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Course 3 chapter 8 volume and surface area answer key A garden apartment that is at the bottom of a 10-step stairway is for lease. A person with a disability that makes it impossible to use stairs asks to see the unit; the landlordA)should advise the prospective tenant of the need for an expensive accommodation that the landlord is unwilling to make.B)should install a motorized seat for the stairway before showing the unit to the prospective tenant.C)should show the prospective tenant the access to the unit and let the tenant decide whether to proceed with the rental.D)should let the prospective tenant know that the unit is unsuitable. The lengths of the sides of a triangle are 11, 7, and 4. Classify the triangle as acute, right, orobtuse. God, shall have a new birth of freedom- and that government of the people, by the people, forthe people, shall not perish from the earth.Abraham Lincoln, Gettysburg Address, 1863How does Lincoln inspire the audience to feel a sense of hope about thefuture in this passage?A. By urging people to increase their "devotion"B. By reminding people of "the great task" before themC. By saying the dead should always be "honored" First person to answer this gets BRAINILEST!!!!Underline the correct expression in parentheses to complete each sentence. 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Selected operating data for the three divisions are as follows:Division A Division B Division CSales revenue $ 1,255,000 $ 920,000 $ 898,000Cost of goods sold 776,000 675,000 652,000Miscellaneous operating expenses 64,000 52,000 53,100Interest and taxes 48,000 41,000 41,500Average invested assets 8,300,000 1,930,000 3,215,000. Wescott is considering an expansion project in the upcoming year that will cost $5 million and return $450,000 per year. The project would be implemented by only one of the three divisions.Required:1. Compute the ROI for each division. (Do not round your intermediate calculations.)2. Compute the residual income for each division. (Loss amounts should be indicated by a minus sign.)3.Rank the divisions according to the ROI and residual income of each.4-a. Compute the return on the proposed expansion project.4-b. Is this an acceptable project? 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Reasons that may motivate MNCs to issue bonds in the international bond markets include a) They may be able to reduce their cost of borrowing by attracting a larger group of investors in a foreign country than in their own home country. b) They may be able to lower their cost of borrowing by issuing bonds in a currency that has lower interest rates. c) They may have a preference to finance a specific foreign project in a particular forcign Furrency and therefore obtain funds where that currency is widely used. d) All the above Why did the Climate Change movement started?? When monet paints haystacks, he depicts the haystacks that are closer to him with a lot of detail but the ones further away with less detail. Monet is using the depth cue of.