The phenyl group of TPCK is structurally similar to regular chymotrypsin substrates.
5. N-Tosylamido-L-phenylethyl, also called tosyl phenylalanyl chloromethyl ketone, (TPCK) irreversibly inhibits chymotrypsin, and is used as to label the active site histidine residue. The COCH2Cl group is the reactive group that binds to the His residue.
a) Why does chymotrypsin bind TPCK?
Answers
Chymotrypsin binds to TPCK because the phenyl group of TPCK is structurally similar to the phenylalanine residue found in regular chymotrypsin substrates.
Chymotrypsin is a serine protease that cleaves peptide bonds adjacent to aromatic amino acid residues, including phenylalanine. Therefore, the phenyl group of TPCK can fit into the active site of chymotrypsin and mimic the binding of a substrate.
Once the phenyl group of TPCK binds to the active site of chymotrypsin, the COCH2Cl group of TPCK reacts with the histidine residue at the active site of chymotrypsin, forming a covalent bond between the two. This covalent bond is irreversible, resulting in the inhibition of chymotrypsin activity.
Overall, the structural similarity of TPCK to regular chymotrypsin substrates allows it to bind to the active site of chymotrypsin and react irreversibly with the histidine residue, leading to the inhibition of chymotrypsin activity.
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Related Questions
Sound waves travel at different speeds
depending on the material they are traveling in.
Which correctly orders how sound waves travel
from slowest to fastest?
Answers
The slowest one is the one that goes up and down the least the fastest is the one that goes up and down the most i dont know how to explain it hopefully this helps
Golgi Body
Cell Membrane
Nuclear Membrane
O
Ribosomes
Vacuoles
Cross-Section of an Animal Cell
Answers
The Golgi body is a cellular organelle that is responsible for modifying and processing proteins and lipids that are produced by the cell. It plays a critical role in the transport and packaging of these molecules for delivery to their appropriate destinations within or outside the cell.
The cell membrane, also known as the plasma membrane, is a thin, semi-permeable barrier that surrounds & encloses the contents of the cell.
The nuclear membrane, also known as the nuclear envelope, is a double-layered structure that surrounds the cell's nucleus, separating it from the rest of the cell.
Ribosomes are small organelles within the cell that are responsible for the synthesis of proteins. They read genetic information encoded in RNA & use it to assemble the correct sequence of amino acids into a functional protein.
Vacuoles are membrane-bound sacs within the cell that play a variety of roles including storage of nutrients, water, and waste products.
Cross-Section of an Animal Cell, this refers to a view of an animal cell as if it were cut in half, showing its internal structure.
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if the mass is 90g and the volume is 100 ml what is the density
Answers
Answer:
168.56
Explanation:
I only have 10 minutes pls. In newborn babies, only the first two lines of defence are ready to fight pathogens. Explain why the third line of defence develops slowly over time.
Answers
When a newborn is born, their immune system is still developing. When the infant gets older, it gets stronger. During our lives, the immune system fights pathogens that might cause disease.
The third task fights germs in what ways?Your immune system's three layer is made up of cells that are specifically designed to eradicate the bacteria that have infected your tissue. The link among innate and adaptive immune system is a special type of cell known as a dendritic cell.
What is the infection's first, second, and third lines of protection?Several coping strategies make the immune system function properly. Infection-prevention measures comprise the primary defence system. Responses to disease that are common to all pathogens make up the protective factor. Immunization against those infections is provided only through the third layer of protection.
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Low blood pressure may cause the net hydrostatic pressure of a capillary to be less than normal. This will result in a(n) ______ net filtration pressure.
Answers
Low blood pressure may cause the net hydrostatic pressure of a capillary
to be less than normal resulting in decreased net filtration pressure.
What is Pressure?This is force applied to a body per unit area and it can be calculated by the
following below:
Pressure = Force/Area
When the net hydrostatic pressure of a capillary is less than normal, the
glomerular blood hydrostatic pressure (GBHP) decreases thereby resulting
in a corresponding decrease in net filtration pressure.
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1. Original DNA: CATATACGCATCTGATTACGTGATTCT CTATA GTATATGCGTAGACTAATGCACTAAGAGATAT
Show the DNA after it has been separated by helicase.
Top Strand:
Bottom Strand:
Answers
Explanation:
gtatatgcgtagactaatgcactaagagatatcatatacgcatctgattacgtgattctctata
The invention of the microscope led to the discovery of the cell by Robert Hooke. While looking at cork, Hooke observed the box-shaped structures, which he called "cells" because they reminded him of the cells (rooms) found in monasteries. This discovery led to the development of the cell theory. Credit for developing the cell theory is usually given to two scientists. Theodor Schwann and Matthias Schleiden. The cell theory was then proposed by Theodor Schwann in 1839. There are three parts to this theory: living organisms are made up of cells, cells are the basic structural unit of all organisms, and all cells come from pre-existing cells. Which of these is supported by the tenets of the cell theory? Select ALL that apply. les )) A) Energy flow occurs within cells. B) Mitosis produces identical daughter cells. C) Living organisms can be unicellular or multicellular. D) DNA is copied and passed between cells during cell division. E) Single-celled bacteria grow and then divide in half to make new bacteria.
Answers
Living organisms are made up of cells, cells are the structural unit of all organisms, cells come from pre-existing cells Energy flow occurs within cells.
What are the main points of cell theory?The main points of cell theory are:
All living things are made up of cells.Cells are the raw building blocks of life.All cells come from preexisting cells through the cycle of cell division.Energy flow occurs within cells.Thus, cells come from pre-existing cells Energy flow occurs within cells.
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List one organism and describe all of its adaptations.
Answers
Adaptation is a mechanism of species to survive and reproduce in their environments, adjusting to selective pressures. Cactus: leaves, stems, spines.
What is adaptation?
In biology, adaptation might be defined as the mechanism of organisms to improve their fitness in the environment in which they live, adjusting to different changes and selective pressures acting on them.
Adaptation involves molecular, physiological, morphological, and behavioral changes.
For these changes to persist and be transmitted from generation to generation, they must increase the individual's fitness. They must increase the individual survival and reproductive probabilities, making it more competitive.
A good and easy to unsderstand example of adaptation is the cactus.
Cactusses are plants adapted to dry and hot environments like deserts, where water availability is scarse and temperatures are high.
To avoid dehydration, cactusses have developed wide palmated or cilindirical stems and reduced or vestigial leaves.
They use stem tissues to store water. Vestigial or reduced leaves to avoid transpiration and water loss.As their leaves are not developed, their stems photosynthetize to produce organic compounds.
Some species are very rich in water and nutrients, so they turn to be covetted by other species. Animals living in the same environment look for them as a source of food.
To avoid predation, cactusses have developed large and numeros spines that are leaves modifications. This is another adaptation to avoid being eaten by animals and avoid loosing water through leaves.
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Which of the following is abundant in plant cells, but greatly REDUCED in animal cells? A. lysosome B. nucleus C. vacuole
Answers
Answer:
C). Vacuoles
Explanation:
Vacuoles are organelles found both in plant and animal cells. However, these organelles are greatly reduced in animal cells . Vacuoles are organelles that function to store substances
Hi, could someone tell me what should be in the blank space of my concept map about the cell membrane?
Answers
A key defining feature of endocrine pathways is that- they elicit rapid and robust changes to the body's physiology the hormones bind to receptors located on the plasma membrane glandular cells of neurons release hormones into the blood all of these options are true
Answers
A key defining feature of endocrine pathways is that they elicit rapid and robust changes to the body's physiology. Endocrine pathways are a vital part of the human body and are responsible for the communication and regulation of body functions. Endocrine pathways have distinct characteristics that distinguish them from other body pathways.
The hormones, which are the chemical signals of endocrine pathways, are released by glandular cells into the bloodstream, from which they reach their target organs or tissues.The hormones bind to specific receptors located on the plasma membrane of their target cells and exert their effects by initiating a cascade of intracellular signaling pathways. The binding of a hormone to its receptor results in changes in gene expression, metabolism, or other physiological processes that are critical to the regulation and homeostasis of the body.
The response to hormone signaling is usually rapid and robust, which allows for quick adaptation to changes in the environment. In conclusion, the answer to the question is that a key defining feature of endocrine pathways is that they elicit rapid and robust changes to the body's physiology.
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which of the following statements regarding a dna double helix is always true?
A double helix is the predominant three-dimensional structure of most forms of RNA.
b) tRNA transfers the base sequence of DNA to the ribosome.
c) mRNA translates the base sequence of DNA for use in protein synthesis.
d) Hydrogen bonding within the same strand of RNA is necessary to maintain its three dimensional structure.
Answers
Among the given options, the following statement that is always true regarding a DNA double helix is:c) mRNA translates the base sequence of DNA for use in protein synthesis.
DNA or Deoxyribonucleic acid is the genetic material that exists in all cells. It contains all the genetic information necessary for the development and functioning of all living things. DNA is a molecule made up of two strands of nucleotides, which spiral around each other to form a double helix. The structure of DNA is double-stranded, with each strand consisting of nucleotides joined by phosphodiester bonds.
Among the given options, the following statement that is always true regarding a DNA double helix is:c) mRNA translates the base sequence of DNA for use in protein synthesis.The mRNA carries the genetic information encoded in the DNA to the ribosomes, where the proteins are synthesized. The mRNA base sequence is complementary to the DNA base sequence, which allows the information to be accurately translated. Therefore, the statement "mRNA translates the base sequence of DNA for use in protein synthesis" is always true regarding a DNA double helix.
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because all animals must take in nutrients from their environment and digest their food internally, the term applied to the nutritional mode of animals is photoautotrophic. photoheterotrophic. chemoautotrophic. phagocytic. heterotrophic.
Answers
Heterotrophic , Autotrophs are creatures that create their own food through photosynthesis, whereas heterotrophs cannot prepare their own food and must rely on autotrophs for sustenance."
Herbivores, omnivores and carnivores, and detritivores are the three categories of heterotrophs. Heterotrophs live on the second and third levels of food chains, feeding on autotrophs (second level) or autotrophs and other heterotrophs (third level) (third level).
Parasitic nutrition is a type of heterotrophic feeding in which an organism survives on or feeds on the remains of another living creature. Parasites are organisms that live within the host organism and obtain sustenance from it.
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20 BRAINIES!! HURRY I HAVE 15 MINUTES!!! We breed some pitbulls, we have a mom who has brown hair and the dad has brown hair. There are 4 puppies in the litter, 3 of them all have brown hair and 1 puppy has black hair. Use the punnett square as evidence to tell me which trait is dominant and which is recessive.
Answers
Answer:
Brown is dominent and black is recessive.
Explanation:
Three of the four puppies have brown hair and only one puppy has black hair.
Answer:
6 pupies
Explanation:
Plant reproduction requires the presence of auxins, as well as a large amount of sugar for energy. Which two main
plant tissues work together to release sugar and carry hormones so that reproduction can take place?
leaves and dermal
stems and ground
dermal and vascular
C ground and vascular
Answers
The two main plant tissues which work together to release sugar and carry hormones so that reproduction can take place are ground and vascular.
What is a vascular tissue?In plants, vascular tissues are tissues that act to transport nutrients to different parts of the plant.
In higher plants, vascular tissues include the plant phloem and the plant xylem.
In conclusion, the two main plant tissues which work together to release sugar and carry hormones so that reproduction can take place are ground and vascular.
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Analyze the diagram below:
According to the model represented in the diagram, which of the following would cause the cell to not express the lacZ, lacY, and lacA sequences?
Binding the RNA polymerase to the gene
Preventing the repressor from binding to the lac operon
Removing the inducer
Transcribing the lacl sequence
Answers
Answer:
Transcribing the lacl sequence
Explanation:
lacZ, lacY, and lacA sequences are the structural genes, which needs to be expressed in order to produce their proteinous enzymes required for the breaking down of lactose sugar. The transcription of these three genes must occur with the aid of RNA polymerase binding to them.
However, a gene sequence called lacI encodes information for an repressor, which when expressed can inhibit the expression of the genes lacZ, lacY, and lacA. Hence, the TRANSCRIPTION OF THE LACL SEQUENCE cause the cell to not express the lacZ, lacY, and lacA sequences.
Answer: removing the inducer
Explanation: all sequences need an inducer present in order for them to be expressed
Which could be the entire inten al over which the
fonction is positive?
-2
-3
-2
-1
2.1
1
2.
3
2
2
0
-8
-10
-20
Answers
Answer:
-3 -2
Explanation:
two negatives multiplied are positive
negative times a positive is negative
0 times any number is 0
The rock cycle describes the processes and transitions through geologic time of the three rock types: sedimentary, igneous and ______. Rocks at the Earth's surface are subject to ______ and ______, transforming into sediment that is then deposited and undergoes _______ and _____, turning into a sedimentary rock through a process call"_______". Rocks in the subsurface are subject to increasing pressure and temperature with depth. Rocks that are exposed to high height and or pressure, but do not melt, undergo ______.When rocks melt, they form _____. When they cool, they ______ to form igneous rocks.
Answers
The rock cycle is a fundamental concept in geology that describes the interrelated processes and transitions that occur over time to the three major types of rocks: sedimentary, igneous, and metamorphic.
Rocks at the Earth's surface are constantly subjected to weathering and erosion, breaking them down into sediment that is transported and deposited elsewhere. This sediment then undergoes compaction and cementation to form sedimentary rocks through a process called "lithification." In contrast, rocks in the subsurface undergo metamorphism as a result of increased pressure and temperature. When rocks melt due to high temperatures, they form magma or lava. Upon cooling and solidification, these molten rocks become igneous rocks. This cycle continues as rocks are constantly being transformed and recycled, providing valuable insights into Earth's geological history and evolution.
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One of the largest and oldest organisms on earth is located in fish lake and nation, forest, in utah.pando is an 80,000 year old grove of aspen trees that cover 100 acres. Although it looks like a forest, DNA analysis of several of the trees has confirmed it is really just one huge organism. Therefore the trees must have been reproduced
Answers
Pando aspen grove in Utah is an immense, genetically identical organism consisting of interconnected aspen trees spanning 100 acres and estimated to be around 80,000 years old.
One of the largest and oldest organisms on Earth, known as Pando, is located in Fish Lake National Forest in Utah. Pando aspen grove is an 80,000-year-old grove of aspen trees that covers approximately 100 acres. While it appears to be a forest, DNA analysis of several of the trees has revealed that they are genetically identical, confirming that Pando is actually one immense organism. The trees of Pando have been reproduced through a process called vegetative reproduction, where new shoots and stems emerge from the existing root system. This unique reproductive strategy has allowed Pando to persist and expand over thousands of years, making it a remarkable example of the interconnectedness and longevity of living organisms.For more questions on Pando aspen grove:
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If we call the amount of DNA per Genome "x", name a situation or situations in diploid organism in which the amount of DNA per cell is:
a. x
b. 2x
c. 4x
Answers
a: X amount of DNA per cell in haploid organisms (gametes) like sperms and eggs. b: 2X amount of DNA per cell in diploid organisms (diploid cells), during G1 or G2 phases of the cell cycle. c: 4X amount of DNA per cell in diploid organisms, during M phase or mitosis. It is also called 2C, which is the amount of DNA in two chromosomes sets (one maternal and one paternal) in a cell.
DNA (deoxyribonucleic acid) is an organic molecule that carries genetic information in most living organisms. DNA consists of two chains that coil around each other to form a double helix. The amount of DNA in a cell varies based on the organism, the cell type, and its stage of development.
Given the above conditions, we can say that the amount of DNA per cell varies based on the type of cell and its stage of development. DNA replication is the process in which a cell makes an identical copy of DNA, which occurs before mitosis (cell division) in diploid cells. The amount of DNA per cell doubles during the S phase of the cell cycle.
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Which organelle is involved in generating vesicles destined for the cell membrane?
Answers
WILL GIVE BRAINLIST TO BEST ANSWER HELP TIMED!
Which statement BEST summarizes the effects that the Irish Potato Famine and Dust Bowl had on the respective populations of Ireland and the United States?
A. The populations of both areas increased as people found more reliable sources of food.
B. The populations of both areas decreased as people died from starvation or moved to other areas.
C. The populations of both areas remained stable until the disasters were over, then increased immediately afterwards.
D. The populations of both areas were relatively unaffected and continued to grow exponentially.
Answers
The populations of both areas decreased as people died from starvation or moved to other areas.
What is a famine?The term famine has to do with a period of extreme scarcity of food. It may be caused by natural disaster or by the loss of arable land due to some other factors. The time of famine is always characterized by a lot occurrences and even death of people.
The Irish Potato Famine and Dust Bowl led to catastrophic loss of the yield of crops forcing many to abandon their livelihoods in the midst of the famine across Ireland and the United Kingdom.
The statement which best summarizes the effects that the Irish Potato Famine and Dust Bowl had on the respective populations of Ireland and the United States is; the populations of both areas decreased as people died from starvation or moved to other areas.
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a researcher is studying transcription in cultured human cells. after she treats these cells with a special culture medium, the human cells begin to divide. in these actively dividing cells, genes encoding which of these rnas will be transcribed the most in the nucleus?
Answers
Answer:
tRNAs and rRNAs
Explanation:i did this out of my own will hope it helps though
should fracking be used to release natural gas and oil ?
Answers
Explanation:
Fracking is the introduction of substances into a formation in order to increase they pore pressure and to increase natural drive of hydrocarbons.
Fracking has several environmental issues associated with it;
Fracking leads to air pollution in case of blowout of gas pressure in formations, particles and dusts can become blasted into the environment. Proppants in fluids channeled into formations can lead to ground water contamination. In areas where fracking is done, there might be an exposure to harmful chemicals. Destruction of the natural habitats of animals.How is the law of conservation of mass applied to ecology?.
Answers
Answer:
The law of conservation of mass states that the total amount of mass remains constant in a system. In ecology, this means that when an organism is eaten, its mass is conserved. Some of the organism’s mass is used to make new proteins, and some of it is passed as waste in the form of urine or feces.
Explanation:
Answer:
The law of conservation of mass states that the total amount of mass remains constant in a system. In ecology, this means that when an organism is eaten, its mass is conserved. Some of the organism’s mass is used to make new proteins, and some of it is passed as waste in the form of urine or feces.
Explanation:
Please answer fast!
worth 100 points
Answers
Answer:
self feeder; E from sun or chemicals - autotrophs
has a nucleus & membrane-bound organelles - eukaryote (5)
the smallest taxonomic division - species (4)
no nucleus or membrane bound organelles - prokaryote (6)
one organism living inside another, both benefit - mutualism
two term - binomial (1)
Explanation:
What are the advantages of planting many kinds of trees?
Answers
Answer:
trees give oxygen to humans and animals Wich they need to breath in order to survive, by planting many kinds of trees the rare and the species that are going extinct can be preserved and trees also protect the land from salinity and soil degradation, they also protect the land from floods.
Ice core samples taken from Antarctica have been used to estimate changes in surface temperatures and the atmospheric concentrations of carbon dioxide and methane. This data indicates that when the temperature is relatively warm, the amounts of carbon dioxide and methane are _________
Answers
Answer:A) relatively high(positive correlation)
Explanation:just took pretest
The temperature changes by – 4°F every hour for 3 hours. What is the total
temperature change in 3 hours? How does the number line above show this?
Answers
Answer: In three hours it would be -12 degrees
Explanation: The number line will show a constant change of the temperatures dropping every hour
Hope this helps
Question 14 (2 points) The process of evolution that involves a change in the DNA sequence that leads to evolutionary change is called natural selection. O mutation. genetic drift. migration.
Answers
The process of evolution that involves a change in the DNA sequence that leads to evolutionary change is called a mutation.
A mutation is a sudden and lasting alteration in the DNA sequence that can influence genetic variation. Changes in the DNA sequence can influence phenotype, which may or may not have an effect on an organism's fitness. Mutations occur spontaneously, either from errors in DNA replication or from exposure to mutagenic agents. Mutations may happen in either coding or non-coding regions of the DNA, and they can be either silent or expressed.
Evolution is a natural process that results in the gradual change of inherited characteristics in populations over generations. It is the process of alteration in the inherited characteristics of species over successive generations. In other words, it is the process of gradual changes that happen to species over time as they adapt to their environments. It can be defined as a change in the gene frequency in a population over time.
Types of Evolution 1. Natural Selection 2. Genetic Drift 3. Gene Flow 4. Mutation 5. Non-Random Mating 6. Admixture 7. Mutation Pressure 8. Genetic Draft 9. Bottleneck and Founder Effect 10. Sexual Selection the process of evolution that involves a change in the DNA sequence that leads to evolutionary change is called a mutation.
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