the most common disease associated with the endocrine system is diabetes. there are multiple types of diabetes. in which type does the patient's body does not use insulin efficiently

Answers

Answer 1

Having type 2 diabetes, which is characterised by a high blood sugar (glucose) level, is a chronic (lifelong) illness. The most prevalent kind of diabetes is type 2.

Which form of diabetes doesn't create insulin?

Your pancreas either doesn't create any insulin or makes very little if you have type 1 diabetes. Blood sugar can be used as fuel by your body's cells with the aid of insulin. In the absence of insulin, blood sugar cannot enter cells and accumulates in the bloodstream. The majority of diabetics (90–95%) are type 2. It takes years to develop, and adults are typically diagnosed with it (but more and more in children, teens, and young adults). If you are at risk, it is crucial to have your blood glucose tested because you might not exhibit any symptoms. Diabetes develops when the pancreas, a gland located behind the stomach, either produces insufficient amounts of the hormone insulin or when the body has trouble utilising it.

To Know more about Diabetes Visit:

brainly.com/question/18791386

#SPJ1


Related Questions

The physician orders a medication to be given 30 MG/KG to be given in two equally divided doses for a child who weighs 70 pounds what is the daily amount to be given

Answers

Answer:

Two doses of 476,2716mg.

Explanation:

The information that we have is:

Dosis: 30mg/kg. Child's weight: 70 pounds.The number of doses: two.

First, we have to convert pounds to kilograms using the rule of three.

70 pounds x 0.453592 kg = 31.75144 kg

1 pound

Now we know that a child needs 30 mg of the medication per kilogram, so for 31.75144 kg, how much medication the child needs?

We have another rule of three

30mg x 31.75144= 952.5432 mg

1kg

The total dose for a child that weighs 70 pounds is 945mg. As he needs two equally divided doses, we have to divide the dose in half.

945mg÷2= 476.2716 mg

Hippocrates, an ancient greek philosopher, is often referred to as the ______________ of medicine.

Answers

Answer: Father of medicine


…………

Noctissssss where are you??????

If you don't know who noctis is don't answer plz

Answers

Answer:

Hey Elesis im here what do you wan't me for????

^^^^^^^^^ Ik u said Dont answer but I did... anyways bye ur person already answered

the article begins by citing a study sponsored the national institutes of health that showed 68% of americans are magnesium deficient. what year was the cited article published?

Answers

The article begins by citing a study sponsored by the National Institutes of Health that showed 68 percent of Americans are magnesium deficient and the cited article was published in 2005.

What is magnesium deficient ?

The cellular uptake of K from the blood depends on magnesium. A patient's ailment will get worse as a result of cellular uptake of K. Supplemental forms of atomic number 30 at high dosages prevent metal absorption. Contrarily, a B vitamin will decrease cellular uptake of metal.

The National Institutes of Health is the main U.S. government agency responsible for medical specialty and public health analysis. It is unsurprisingly referred to as agency (with each letter pronounced separately). The United States Department of Health and Human Services currently oversees it, and it was undoubtedly backed in the late 1980s.

Learn more about Magnesium here:

https://brainly.com/question/5759562

#SPJ4

Complete the sentence.
Standard precautions make up the main component of______ asepsis.

Answers

Standard precautions make up the main component of medical asepsis.

What is medical asepsis?

Medical asepsis, also known as clean technique, refers to the practices that are used to reduce and prevent the spread of infection within a healthcare setting.

This includes hand hygiene, use of personal protective equipment, proper handling and disposal of contaminated materials, and regular cleaning and disinfecting of surfaces and equipment.

Standard precautions are a set of specific medical aseptic practices that are used to prevent the transmission of pathogens in all healthcare settings, regardless of the patient's diagnosis or presumed infection status.

These precautions include hand hygiene, use of personal protective equipment, respiratory hygiene and cough etiquette, safe injection practices, and proper handling of medical waste.

More on medical asepsis can be found here: https://brainly.com/question/30641990

#SPJ1

The nurse knows early in shock, blood is shunted away from the kidneys. How long can the kidneys tolerate reduced blood flow before cells begin to die

Answers

The kidneys can tolerate reduced blood flow before the cells begins to die for about 1 hour before sustaining permanent damage.

Kidneys are the essential organ involved in purification of fluids present inside the body. During shunting, the blood enters the body through venous system without passing through the lung tissues. Renal arteriovenous shunts are the rare pathologic interaction between the renal arteries and veins without interconnecting capillaries. Human kidneys can tolerate reduced blood flow for about an hour only if their are no functional losses in the body. In shocks, the person does not get adequate oxygen, or fluid flow and drug therapy are not much effective.

Learn more about arteriovenous at:

brainly.com/question/29569061

#SPJ4

Mr. Diaz continued working with his company and was insured under his employer’s group plan until he reached age 68. He has heard that there is a premium penalty for those who did not sign up for Part B when first eligible and wants to know how much he will have to pay. What should you tell him?

Answers

I should tell him that since Mr. Diaz maintained continuous coverage under his employer's group plan, he will not be subject to any penalties.

The premium is the sum that the insured pays on a regular basis to the insurer to cover his risk. The risk is transferred from the insured to the insurer under an insurance arrangement. The insurer levies a fee known as the premium in exchange for taking on this risk.

The term "premium penalty" refers to the fine imposed under this part and ERISA section 4007 for failure to pay a premium in full and on time. For the number of full, uncovered months you were without Part D or creditable coverage.

To learn more about Premium visit: https://brainly.com/question/13724529

#SPJ9

Mrs. Chou likes a Private Fee-for-Service (PFFS) plan available in her area that does not include drug coverage. She wants to enroll in the plan and enroll in a stand-alone prescription drug plan. What should you tell her?

Answers

Answer:

She could enroll in a PFFS plan and a stand-alone Medicare prescription drug plan.

Explanation:

To maximize absorption of digoxin, the nurse would instruct the patient to take the drug?

Answers

To maximize absorption of digoxin, the nurse would instruct the patient to take the drug on an empty stomach.

Digoxin is absorbed, mainly in the small intestine, and certain drugs that can reduce digoxin absorption include antacids, magnecholestyramine, etc.  

Digoxin is a class of drug called a cardiac glycoside. Their function is to reduce the heart rate and improve the filling of ventricles (chambers of the heart) with blood. It is generally prescribed to people with atrial fibrillation, who have irregular heartbeats and as a result, a different quantity of blood is pumped out with each beat.

To learn more about digoxin here

https://brainly.com/question/15180878

#SPJ4

which standard does qsen identify? A. Evidence-based practice B. Informatics C. Nursing research D. Patient-centered care E. Quality Improvement

Answers

QSEN identifies multiple standards, including evidence-based practice, informatics, patient-centered care, and quality improvement.

QSEN(Quality and Safety Education for Nurses)

QSEN, which stands for Quality and Safety Education for Nurses, identifies several nursing competencies that are essential to providing safe and effective care to patients.

These competencies include patient-centered care, teamwork and collaboration, evidence-based practice, quality improvement, safety, and informatics.

Therefore, QSEN identifies multiple standards, including evidence-based practice, informatics, patient-centered care, and quality improvement.

Learn more on QSEN:https://brainly.com/question/30451418

#SPJ1

what’s the prefix for emesis?
what’s the suffix for emesis?

Answers

Answer:

1. unemesis

2. emesisly

When someone's core body temperature is dropping, what is oftentimes the most obvious indicator that they have transitioned from mild to moderate hypothermia.

Answers

The most obvious indicator of going from mild to moderate hypothermia is that shivering stops.

Hypothermia occurs as the temperature drops below normal levels. In humans, hypothermia is experienced if the temperature is below 36°C. Moreover, hypothermia is classified into:

Mild hypothermia.Moderate hypothermia.Severe hypothermia.

Each of these types is related to specific symptoms and therefore their treatment is slightly different.

In the case of moderate hypothermia, the symptoms include:

Slower heartbeat and breathing.Lack of coordination.Fatigue

This type differs from mild hypothermia (previous stage) because in mild hypothermia the person shivers but in moderate shivering stops.

Learn more about Hypothermia in: https://brainly.com/question/6552936

Starting a new exercise regimen without consulting a doctor first can be dangerous, especially if you have previous injuries. Please select the best answer from the choices provided. T F

Answers

The answer is true....

It is true that initiating a new exercise regimen without consulting a doctor first can be dangerous, especially if you have previous injuries.

What is exercise?

Any mobility that causes your muscles to engage and necessitates the body to consume calories is considered exercise.

Swimming, starting to run, sprinting, walking, and dancing are just a few examples of physical activities. Being physically and mentally active has been proven to have numerous health benefits.

Before embarking on a new or drastically different exercise regime, consult with a medical professional.

Preexisting circumstances can be identified by medical professionals, and family history can be used to help implement an exercise regime. Before seeking medical advice, one should begin an exercise regimen.

Thus, the given statement is true.

For more details regarding exercise, visit:

https://brainly.com/question/13128077

#SPJ6

The degree of closeness of measurements of quantity to that quantity actual (true) value

Answers

The answer is - Accuracy

For Type A individuals, exposure to stress is especially likely to inhibit organ activity, such as the ________ removing cholesterol and fat from the blood.
Select one:
a. liver
b. thyroid gland
c. pancreas
d. adrenal glands

Answers

For Type A people, exposure to stress is most likely to inhibit organ activity, such as the: (liver) removing cholesterol and fat. Hence, the correct answer is option A.

What is Type A in psychology?

In psychology, human personality is classified into four categories:

Type A individuals have a behavior pattern associated with high achievement, impatience, and competitiveness.Type B individuals are associated with patient, laid-back, and flexible behavior.Type C individuals are associated with accuracy, rationality, and logic.Type D individuals are associated with security, repetitiveness, and longevity.

As mentioned above, Type A individuals have high competitiveness and are impatient. It makes them more prone to stress-related illnesses such as high blood pressure, inhibition in organ activity such as liver, etc.

Learn more about personality psychology here https://brainly.com/question/29507926

#SPJ4

what are some of the purposes of a post-mortem? check all that apply.
a. To learn from and adapt processes for higher efficiency
b. to understand the cause of mistakes and how to prevent them
c. to foster a culture where it's ok to make mistakes

Answers

The purpose of post-moterm is to understand the cause of mistakes and how to prevent them.

A post-moterm, which is also called an autopsy  an examination of the body done after the passing of the individual.

When the post-moterm of a body is done, it gives us a brief understanding of what went wrong in the body and what was the cause of the death or how did the death caused.

By learning about how and what happened, we can understand the causes of the mistakes and  we can prevent them in future.

A major experiments and crucial information is obtained from the post-moterm report of the body. This useful information is used in future to make medicines and surgical methods.

To know more about Post-Moterm, visit,

https://brainly.com/question/21123962

#SPJ4

When preparing the room for an infant with bronchiolitis, which equipment is most important?
A tracheostomy set
IV atb
A metered dose inhaler
Oxygen tubing and face mask

Answers

When preparing the room for an infant with bronchiolitis, the most important equipment is oxygen tubing and a face mask.

Bronchiolitis is a respiratory condition that affects infants and young children and is characterized by inflammation and congestion of the small airways in the lungs. The condition is most often caused by a viral infection, usually the respiratory syncytial virus (RSV).

It is a common condition in children under the age of two. Infants and young children are more likely to develop bronchiolitis as their airways are narrower and less able to cope with inflammation and mucus build-up. In bronchiolitis, the inflammation and mucus buildup can cause wheezing and difficulty breathing. In infants with bronchiolitis, the most important equipment when preparing the room is oxygen tubing and a face mask.

This is because these children often experience difficulty breathing, and oxygen support may be necessary to help them breathe more easily. Oxygen therapy with a face mask is typically the first line of treatment for children with bronchiolitis who have difficulty breathing. This treatment may be administered in the hospital or at home, depending on the severity of the child's condition.

To learn more about bronchiolitis

https://brainly.com/question/7827873

#SPJ11

Externally defined principles that govern standards of behavior within a group are known as ____.

Answers

i think its moral principles

Externally defined principles that govern standards of behavior within a group are known as Ethics.

What is a Behavior?

Behavior may be defined as a type of observable response of an organism with respect to external or internal stimuli. It remarkably contributes to the differential expression of organisms.

Ethics is generally the regulations of moral principles and values that must be considerably governed by the behaviors of a person or group with respect to what is right or wrong according to the situation that arises.

The branching of ethics deals with the conduction of each and every activity of an individual with respect to their behavior. The core ethical principles are beneficence, justice, nonmaleficence, and autonomy.

Therefore, ethics is externally defined principles that govern standards of behavior within a group.

To learn more about Ethics, refer to the link:

https://brainly.com/question/13969108

#SPJ2

The buffers that adjust to control acid-base balance is

Answers

Answer: Plasma proteins, phosphate, and bicarbonate and carbonic acid buffers.

Explanation: The kidneys help control acid-base balance by excreting hydrogen ions and generating bicarbonate that helps maintain blood plasma pH within a normal range.

8
Type the correct answer in the box. Spell all words correctly.
Point
is the vertex of the angle marked in the figure.

Answers

We need the table, in order to complete the problem.

Acategorical term for a word part that is added to a root word to change or modify its meaning is called a(n)
A word part added to the beginning of a word and that is often used to indicate location, time, or present status is
called an)
A word part that is added to the ending of a root word to form a new term is called the
A root word with an added vowel at the end that makes it easier to pronounce is called a

Acategorical term for a word part that is added to a root word to change or modify its meaning is called

Answers

1) both prefix and suffix (affix)
2) prefix
3) suffix
4)combing form

What component of muscular fitness training is the equivalent of intensity in aerobic fitness training

Answers

Answer:

Isotonic

Explanation:

Pretend you could shrink yourself down to the size of a cell and take a tour of one body system from this unit. Which would you choose and why? Explain why you find that body system especially fascinating, surprising, confusing, or disgusting.

Answers

The digestive system is the one which is chosen and the fascinating thing about this type of system is the conversion of various food substances into nutrients which are assimilated into the body system.

What is Digestive system?

This type of system comprises of cells, tissues etc which are involved in the breakdown of food into smaller parts which is then absorbed by the body.

Digestive system was chosen because it is fascinating in terms of how there are different types of enzymes which are substrate specific and are involved in the conversion of the food into nutrients which are used by the body for its daily activities.

The disgusting part of the digestive system however is the formation of the chyme and also the formation of feces in the large intestine after several processes have taken place.

Read more about Digestive system here https://brainly.com/question/956634

#SPJ1

what is non specific resistance?​

Answers

Non-specific resistance is our body's line of protection against all infections. It comprises the generation of antimicrobial compounds, phagocytosis, inflammation, fever, and skin and mucous membrane.

The non-specific resistances are:

Skin and Mucus Membranes: The body's initial line of defense against pathogen invasion is provided by the skin and mucus membranes. It functions as a chemical agent as well as a mechanical barrier.Phagocytosis: Phagocytosis is the process by which a cell ingests bacteria or any other type of particle matter. Some protozoa, like amoebas, use it as a form of nourishment.Inflammation: When body tissues are damaged, it causes inflammation in the nearby tissues. However, there are a number of factors that can induce tissue damage, including physical ones (such as heat, light, electricity, or sharp objects), pathogen infections, chemicals (acids, bases, gases), etc.Fever: Fever is an excessively high body temperature brought on by bacterial or viral illness, bacterial toxins, or both. It goes without saying that the hypothalamus, a brain region, regulates body temperature. As a result, it is sometimes referred to as the body's thermostat because it keeps the internal temperature at 37 °C (98.6 °F). The hypothalamus is affected by antigens, raising body temperature.Antimicrobial Substances: The body also produces several antimicrobial substances after a microbial infection, such as complement, properdin, and interferon proteins.Interferon: For viral replication, host cells are absolutely necessary. However, the host cells may or may not sustain damage during the process of replication. It is extremely challenging to prevent the virus from replicating without harming the host cells. When certain animal cells are stimulated, they create interferons (IFN), a type of antiviral protein. Interferons are utilized nowadays to promote immunity.

Learn more about non-specific resistance like pathogens here:

https://brainly.com/question/14139613

#SPJ9

19) What is a traveling Guide?
a) something that don't move
b) something that move
c) stay in between
d) In the back of the head

Answers

Answer:

d is the answer I think sry if it's worng

This question is strange but I’ll say b

A positive correlation indicates that

Answers

A positive correlation exists when two variables move in the same direction as one another. A basic example of positive correlation is height and weight—taller people tend to be heavier, and vice versa. In some cases, positive correlation exists because one variable influences the other.

In statistics, a positive correlation shows that changes in one variable will relate to the same type of changes in a second variable. The data is usually displayed in a scatterplot, which shows the linear relationship between variables in a positive correlation graph.

a toothpaste with high abrasive is recommended to remove plaque. T/F

Answers

Answer:

T

Explanation:

False. A toothpaste with high abrasives is not recommended to remove plaque. In fact, using a toothpaste that is too abrasive can actually damage the enamel on your teeth.

Plaque is best removed through regular brushing and flossing, as well as regular dental cleanings. It is important to choose a toothpaste that contains fluoride, which helps to strengthen tooth enamel and prevent cavities. Additionally, some toothpastes may contain ingredients such as triclosan or hydrogen peroxide, which can help to reduce plaque and prevent gum disease. It is always best to consult with your dentist to determine the best toothpaste for your individual needs.
False. A toothpaste with high abrasiveness is not recommended to remove plaque. Abrasive toothpastes can damage tooth enamel and gum tissue, leading to dental problems. Instead, choose a toothpaste with a moderate level of abrasiveness and fluoride to effectively remove plaque while protecting your teeth and gums. Additionally, proper brushing technique and regular dental check-ups are essential for maintaining good oral hygiene.

To learn more about toothpaste visit;

https://brainly.com/question/862073

#SPJ11

6. CPG 101 V2 includes a six-step planning process. These steps include all of the following EXCEPT:

Answers

The Consumer Products Good (CPG) 101 V2 is the FDA guideline that provides the basic requirements and best practices for good manufacturing practices (GMPs) for the manufacturing of human food, animal food, dietary supplements, and cosmetics.

These guidelines provide a reference for manufacturers to follow to ensure that their products meet the required quality standards and are safe for human consumption. The six-step planning process of CPG 101 V2 includes:

Step 1: Preliminary Steps

Step2: Scope

Step 3: Hazard Analysis

Step 4: Preventive Controls

Step 5: Verification

Step 6: Record-keeping and Documentation

The steps mentioned above outline the CPG 101 V2's planning process, which ensures the production of safe, high-quality food products.

The FDA requires all food manufacturers to implement these steps to ensure that the products are manufactured under suitable conditions, maintain quality, and are free from contaminants. However, the six-step planning process of CPG 101 V2 does not include identifying the location of the production facility. Although, manufacturers should ensure that the facility they choose meets the requirement of FDA's good manufacturing practice.

Therefore, the step excluded from the planning process is to identify the location of the production facility. The six-step planning process is a robust guide for manufacturers to produce safe food products that meet the quality standards.

Know more about dietary supplements here :

brainly.com/question/31535425

#SPJ8

Handling ready-to-eat salad greens with bare hands exposes food to what potential hazard?
O Time-temperature abuse
Chemical contamination
O Cross-contamination
O Improper cleaning and sanitizing

Answers

Answer:

O improper cleaning and sanitizing

Explanation:

sana nakatulong

Handling ready-to-eat salad greens with bare hands exposes food to Cross-contamination.

Cross-contamination refers to the movement of microorganisms that could be harmful from one host to another. This host can be an object, an animal or a human being and the most popular microorganism that moves this way is bacteria.

If ready-to-eat food is handled with bare hands, there is a chance that bacteria from the hands will move onto the food which is the very definition of cross-contamination.

Contaminated food can be very dangerous health wise because it could lead to food poisoning which can be fatal.

More information on cross-contamination and food poisoning can be found here https://brainly.com/question/1134435 and https://brainly.com/question/23446083.

Depositions are A. written quiestions that must be answered under oath. B. a discovery method for obtaining documentary evidence. C. a discovery method for avoiding the need to prove a fact in court D. a discovery method for obtaining testimony under oath

Answers

Depositions are a discovery method for obtaining testimony under oath. In a deposition, an attorney or representative of a litigant will ask questions of a witness or other party in order to elicit answers from them.

Correct option is C.

When done correctly, depositions are a powerful tool to obtain the evidence and to gather the truth about a case. The questions can be difficult, and the witness must be sure to answer them truthfully. Depositions are conducted outside of a courtroom, typically in an attorney’s office, and they are recorded.

The parties to the case will have to agree on the questions to be answered and the time the deposition will take place. The questions that are asked, and all of the answers provided, become part of the evidence for the case. Depositions help attorneys to prepare their case for a jury, as they can make sure that all the facts will come out in the open.

Correct option is C.

know more about testimony here

https://brainly.com/question/28178609#

#SPJ11

Other Questions
which of the following is true? multiple select question. price elasticity of demand and slope are not always the same along a linear demand curve. price elasticity of demand and slope are the same along a linear demand curve. price elasticity of demand and slope are the same along a non-linear demand curve. price elasticity of demand and slope are not always the same along a non-linear demand curve. Steven found that between 2012 and 2020, as a country's per capita chicken egg consumption increased, the country's divorce rate decreased. Based on this information, which of the following conclusions is valid?O Eating chicken eggs prevents divorces.O Divorces lead to a decrease in per capita chicken egg consumption.O There is a positive association between per capita chicken egg consumption and divorce rate.O There is a negative association between per capita chicken egg consumption '.' and divorce rate The following frequency distribution summarizes the weights of 195 fish caught by anglers participating in a professional bass fishingtournament.Weight (Pounds)Frequency1-3254-6907-9 10-1275 5(a) Calculate the (approximate) sample mean for these data. (Round your answer to 2 decimal places.)Xlbs(b) Calculate the (approximate) sample variance for these data. (Round your answer to 3 decimal places.)S^2 what is the greatest and least number that can be rounded to 120,000 You, Yes Yougo grab a glass of water,sit in front of the mirror and smile.even if you have nothing to smile about, just try it,you'll find something beautiful in you.if you think you're ugly or having a bad hair day,focus on your eyes, i think your eyes are beautiful.don't think so? think again, there is no such thing as ugly eyes.still smiling?STOP!now smile again.notice you're more beautiful when you smile.cool right?You should try it more :)are you scared of anything right now?Are you stressed?Take a sip of water.now before you wipe the water away,see the drops of water on your lips.notice how they shine,even in the tiniest bit of light.they're just like you.you shine no matter what.you'll put up a smile even though you're hurtingyou'll shine even though you're bursting into tears.How do I know?Because you're still here, practising self-care.and you know self-care isn't selfish.you know how to feel and you know how to breathe.You're shining,and I'm very proud of you.(please spread this message forward) Hope is the thing with feathersThat perches in the soul,And sings the tune without the words,And never stops at all,And sweetest in the gale is heard;And sore must be the stormThat could abash the little birdThat kept so many warm.Hope is the thing with feathers,Emily DickinsonIn the first two stanzas of her poem, Dickinson establishes an extended metaphor by comparingsweetness and a gale.hope and a bird in a storm.something heard in a storm and warmth.a tiny bird and warmth. During the month of July, Clanton Industries issued a check in the amount of $845 to a supplier on account. The check did not clear the preparing the July 31 bank reconciliation, the company should: Multiple Choice o Deduct the check amount from the book balance of cash Add the check amount to the book balance of cash. Deduct the check amount from the bank balance ) Add the check amount to the bank balance. Next > 42 of 50 < Prev Prej OPH Plz help me, anyone plz Answer Fast Please!! Find the volume of the cylinder. Use 3.14 for pi. Y is inversely proportional to XX = 3 y=8 Work out Y when x = 8 What is an example of a memo?a. Anna expresses her love through a letterb. The school sent a guideline for the procedure of module retrievalc. Britney sent a les message infoming everyone that the class is concelled next weekenedd. Angela called to inform everyone that the modules are ready The universe began in an incredibly hot and dense state about 13.8 billion years ago. Since this time, it has been rapidly expanding, causing galaxies to move away from one another. Energy in the coldest depths of space can be explained as radiation left behind from the universe's early, more energetic state. plNGSSS CheckMetalAluminumZincIronCopperDensity(g/cm)2.707137.878.966. Use the table above todetermine the identityof a substance with amass of 108 g and avolume of 40 cm.SC.8.P.8.3the substancesthat do not dTherefore, midentifyingpoint and ttable salt.When yhow the pknown tvdo not d Which of the following included a tax on official documents Examine the photograph of German troops. What does the image suggest about the early years of the war? Which term best describes the expression 137 rabbits per square km?. Solve p|5||3|=20 . The solution is p= Apples first-generation ipad was priced at over $800 when it launched in 2010. Three years later the same model was priced at under $300. This change was supported by all of the statements below except. what determines which of the 2 X chromosomes will be methylated? A rectangle has an area of 14y - 63y.a. What are expressions for the length and width where one dimension isthe GCF?pls help.