the lethality of ku86 (xrcc5) loss-of-function mutations in human cells is independent of p53 (tp53)
Answers
The loss-of-function mutations in Ku86 do not require p53 or its involvement to cause lethality in human cells.
The statement you provided suggests that the lethality of Ku86 (XRCC5) loss-of-function mutations in human cells is not dependent on the presence or status of the p53 (TP53) gene. Ku86 is a protein encoded by the XRCC5 gene. It forms a heterodimeric complex with Ku70 (encoded by the XRCC6 gene) to create the Ku protein complex. The Ku complex plays a critical role in DNA repair, particularly in the non-homologous end joining (NHEJ) pathway, which is responsible for repairing double-strand breaks in DNA.p53 is a tumor suppressor protein encoded by the TP53 gene.
This implies that the lethality resulting from Ku86 loss-of-function may be due to other critical functions or interactions of Ku86 that are independent of p53-mediated processes.
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Related Questions
which factor of bacterial adherence is used to bind to host cell surface glycoproteins, glycosphingolipids, or glycosaminoglycans to establish a unique niche within the host? answer choices
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Bacterial adherence uses microbial adhesins to bind to host cell surface glycoproteins, glycosphingolipids, or glycosaminoglycans to establish a unique niche within the host.
Microbial adhesions, also known as bacterial adhesins or bacterial ligands, are proteins or glycoproteins found on the surface of bacteria that are responsible for attachment to host cells.
These adhesins recognize specific receptors on the surface of the host cell, including glycoproteins, glycosphingolipids, or glycosaminoglycans, which are essential for establishing a unique niche within the host.
By binding to these receptors, bacteria can adhere to the host cell surface and avoid being cleared by the immune system, ultimately leading to colonization and infection.
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Please help with answer 3 :)
Answers
Answer:
1) Diffusion : Is the movement of molecules / ions from a region of higher to lower concentration. It may or may not occur across a semi permeable membrane.
In diffusion there is no challenge involved as it is along the concentration gradient, but in active transport movement of molecules occur against concentration gradient ie; from lower to higher concentration.
2) For active transport, energy is vital for movement, in this case protein molecules function as molecular pumps to enable the cell accumulate glucose/ions, against concentration gradient. Here metabolic energy ATP is required.
3)Facilitated diffusion is a type of passive transport in which ions/molecules cross the semi permeable membrane because permeases present in the membrane facilitate the transport.
Like simple diffusion facilitated diffusion doesn't require metabolic energy and simply occurs across the concentration gradient.
4) Osmosis : is movement of water from hypotonic solution (lower concentration) to hypertonic solution (higher concentration) through a semi permeable membrane.
The cell membrane being permeable to water allows to and fro movement of water molecules along the concentration gradient.
Create Your Own Pedigree:
Albert and Betty are married. They both have normal vision. They had 2 daughters and then a son.
Both daughters, Cassie & Debra, had normal vision and never had any children of their own. Their son,
Elliot, was colorblind. Elliot married Fallon who also had normal vision and they had 2 of their own children,
George and then Hailey. Hailey was colorblind but George was not.
Colorblindness is sex-linked recessive (X³). Use the letters X, Y or X² for the genotype. Draw the
pedigree below placing the genotypes for Albert, Betty, Elliott, Fallon and Hailey in their respective shapes.
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To the best of your ability, draw how two populations would be dispersed in each of the three types of speciation. Label each drawing as either "A" for allopatric, "P" for parapatric, or "S" for sympatric.
You may use circles to represent each of the populations.
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Answer: You know, we went over this in class Karra...
Explanation: Review your lessons in class before completing the assessments.
How can changes to the physical or biological components of an ecosystem affect organisms and populations?
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Explanation:
Because population increase the number of people so,their need will increase. Hence it can change to the physical or biological components of an ecosystem.
What role does cellular respiration play in the carbon cycle
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Answer:
the answer is A if not let me know I'll check
Why are brothers and sisters similar? Explain?
please answer and ill give branliest
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What is the term for the site where the muscle attaches that does not move when the muscle contracts?.
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The attachment site at the origin is where the muscle attaches; the attachment site at the insertion is where the muscle attaches but moves during contraction.
The place where muscles connect is known as what?Muscle and bone are joined together by tendons, which are fibrous connective tissues. Muscles can be joined to tissues like the eyeball through tendon connections as well.
The distinction between voluntary and involuntary muscles is that the former can move under conscious control or at the command of the mind, while the latter move automatically or without conscious command. Smooth muscles and cardiac muscles fall within the category of involuntary muscles.
Skeletal muscles with voluntary action are those that can be consciously controlled to contract and relax. Body movement is controlled by these muscles, which are attached to bones.
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If the density of basalt is greater than granite, then what can be determined about its specific gravity?
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Based on the relative densities of basalt and granite, it can be inferred that the specific gravity of basalt is higher than the specific gravity of granite.
The specific gravity of a substance is defined as the ratio of its density to the density of a reference substance.
In the case of rocks and minerals, the reference substance commonly used is water.
Since the density of basalt is greater than granite, it can be determined that the specific gravity of basalt is also greater than that of granite.
Basalt is an igneous rock that is formed from the rapid cooling and solidification of lava.
It is known for its dense and heavy nature, which is primarily due to its mineral composition, including minerals like pyroxene, plagioclase feldspar, and olivine.
These minerals have relatively high densities compared to the minerals found in granite.
Granite, on the other hand, is a coarse-grained igneous rock that is formed from the slow crystallization of magma deep within the Earth's crust.
It is composed mainly of minerals such as quartz, feldspar, and mica.
While granite is a relatively dense rock, its density is generally lower than that of basalt.
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Which of the following is an example of phagocytosis? : A cell takes in large amounts of water. A cell in the thyroid gland secretes a product to the outside. the sodium-potassium pump uses ATP energy to move ions. An amoeba wraps its membrane around a small unicellular organism to eat it.
Answers
Answer:
An amoeba wraps its membrane around a small unicellular organism to eat it.
Explanation:
State one similarity and one difference between parasitic and predatory modes of feeding
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Answer:
One similarity between parasitic and predatory modes of feeding is that both involve the ingestion of other organisms for nutrition. In both cases, the organisms that do the feeding (the parasites or predators) obtain their food from other organisms (the host or prey), which they consume and use to nourish themselves.
One difference between parasitic and predatory modes of feeding is the relationship between the predator and its prey. In predatory feeding, the predator and its prey are typically separate and distinct organisms, and the predator actively hunts and kills its prey for food. In parasitic feeding, the parasite and its host are typically closely associated, and the parasite typically lives on or inside the host, feeding off of its nutrients or tissues. This relationship between the parasite and its host is often harmful to the host, while the relationship between the predator and its prey is typically not harmful (as long as the predator is not over-consuming its prey).
what is photosynthesis
Answers
Answer:
the process plants use to extract energy from sunlight
Explanation:
Which shows the most direct path that carbon can take through the carbon cycle?
plant ® atmosphere ® animal
O animal ® plant ® atmosphere
plant ® animal ® atmosphere
atmosphere ® animal ® fossil fuel
Answers
Answer:
plant animal atmosphere
Explanation:
i took the test on edge and i got the correct answer
Answer:
Your answer is C: plant ® animal ® atmosphere
Explanation:
Hoped this helped :))
2 Lakes have similar abiotic factors of light,temperature,ect. one has a great biodiversity while the other dose not. Acid rain begins to fall in the environment.which lake will have a greater chance of survival?
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Answer:
The one with the grater biodiversity :) hopes it helps
Explanation:
which of the following is an adaptation of seed plants? answer spores vascular tissues flagellated sperm pollen
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Seed plants produces flagellated sperm .
Many primitive gymnosperms have flagellated sperm cells, In many seed plants the use of resistant far-traveling airborne pollen to bring gametes together in a terrestrial adaptation.
Sperms are the male gametes manufactured in pollen grains or microspores. Flagellated sperms mean that the male gametes have the flagella, the organs for movement so they are also known as motile sperms. Hence ,seed plants that have flagellated sperm are Ginkgo and Cycadales.
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I need help I just keep si g different answers to this question
Answers
Answer:
I think your right the first one
Explanation:
♀
Amoeba Sisters Video Recap: Prokaryotic vs. Eukaryotic Cells 7. At the end of the video, there's a vocabulary challenge mentioned. Can you use the vocab to create your own sentences to compare and contrast prokaryotic cells with eukaryotic cells? If you need more space, you can attach an additional sheet of paper.
Answers
Answer:
True nucleus and organelles.
Explanation:
The main difference between Prokaryotic cells and Eukaryotic Cells are given below.
Prokaryotic cells have no true nucleus while Eukaryotic Cells have true nucleus. true nucleus means that membrane is surrounded the nucleus which clearly show the nucleus. Prokaryotic cells have no organelles while eukaryotic cells have organelles which perform specific function in the cell. these organelles are plasma membrane, ribosome, mitochondria, vacuoles, cytoskeleton, plastids and endoplasmic reticulum.
True nucleus and organelles.
What is the difference between prokaryotes and eukaryotes?
The primary distinction between these two types of organisms is that eukaryotic cells have a membrane-bound nucleus and prokaryotic cells do not. The nucleus is where eukaryotes store their genetic information.
Thus, the True nucleus and organelles are the answer.
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A prokaryotic cell has a nucleus. True or false?
Please help please thank u a lot
Answers
Answer:
A prokaryotic cell does not have a nuclues
Explanation:
how i remember it is pro=no(no nucleus)
and a eukaryotic cell you just remember of yourself
our eyes continually scan the visual field because: group of answer choices our visual neurons respond to changing images duplexity theory of vision retinotopic organization of the primary visual cortex rhodopsin of the distribution between rods and cones
Answers
Our eyes continually scan the visual field because most visual neurons respond only to changing images and if retinal images are artificially stabilized i.e, kept from moving on the retina.
For most vertebrates and some molluscs, the retina is the innermost, most light-sensitive layer of tissue in the eye. The retina, which gets a focused, two-dimensional image of the world around us from the eye's optics, analyzes it, and then delivers nerve impulses that carry that processed image to the visual cortex via the optic nerve, is what gives us vision. The retina functions similarly to a camera's film or image sensor in many respects.
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A stroke kills neurons in two waves, first by ____ and second by ____. Group of answer choices Understimulation; overstimulation
Answers
A stroke kills neurons in two waves, first by overstimulation and then by understimulation.
A stroke is an acute reduction in blood flow within the brain. Stroke rapidly destroys neurons in the brain areas of lowest blood flow, resulting in an infarct of necrotic brain tissue.
What happens in overstimulation?
Overstimulation is a condition in which there’s too much sensory input for the brain to handle. It can be a form of physical or emotional discomfort and feeling like the brain is frozen or unable to think or process anything that’s happening. Overstimulation occurs when a person surpasses their threshold for sensory input.
What happens in understimulation?
Understimulation occurs when there is not enough sensory input or feelings to keep you engaged with your surroundings. When there is no brain activity after the stroke, it can leave a person unable to respond, or in a sleep-like state. This can trigger unconsciousness or coma and means that important parts of the brain are not working well.
Therefore, a stroke kill neuron, first by overstimulation and second by understimulation.
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please please help i will give brainalist and extra points
Answers
Answer:
I'm pretty sure the answers for this is D, C, and B.
‼️⁉️need answer ASAP ‼️⁉️Which property describes a mixture? Cannot be separated by physical methods. It has a Single Chemical composition. It cannot have more than one state of matter. It cannot be described by a chemical symbol or formula.
Answers
Answer:
Explanation:
id :- 257 473 5835 password:- 1234
Answer:
D.
Explanation:
Space review part 2, I need help on this! Giving brainliest to best answer
Answers
Answer:
terrestrial: mercury, venus, earth, & mars
gas/ice giants: jupiter, saturn, uranus, & neptune
Explanation:
Answer:
terrestrial;mercury,venus,earth&mars
gas/ice giants;jupiter,saturn,uranus & neptune
Explanation:
How is ATP is involved in making sugars in photosynthesis?
Answers
Explanation:
For plants, this is a particularly important source of ATP because ATP is also required for the first glucose synthesis process. Without a supply of ATP produced by photosynthetic processes, plants would be caught in a "catch-22" position where they would need to produce glucose in order to manufacture ATP.
Based on cell theory, which of these answer choices would describe one reason a virus is considered nonliving?
Answers
Answer:D
Explanation:
I just did it
what is the common structure of a bacterial promoter with respect to consensus sequences
Answers
The common structure of a bacterial promoter with respect to consensus sequences is that it typically contains two important regions, the -10 and -35 regions, which are located 10 and 35 base pairs upstream of the transcription start site, respectively.
These regions are recognized by RNA polymerase and are necessary for the initiation of transcription.
The -10 region, also known as the Pribnow box, has a consensus sequence of TATAAT. The -35 region has a consensus sequence of TTGACA. These consensus sequences are not always identical in every bacterial promoter, but they are usually similar enough to be recognized by RNA polymerase.
In addition to these two regions, bacterial promoters may also contain other regulatory elements, such as operator sites, which are recognized by transcription factors that can either activate or repress transcription.
Overall, the structure of a bacterial promoter is important for the regulation of gene expression and the initiation of transcription.
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itaconate: the poster child of metabolic reprogramming in macrophage function. o’neill laj1, artyomov mn2. nat rev immunology, 2019
Answers
The statement refers to an article titled "Itaconate: The poster child of metabolic reprogramming in macrophage function" by Luke A.J. O'Neill and Maxim N. Artyomov, published in Nature Reviews Immunology in 2019.
The article explores the role of itaconate, a metabolite derived from the tricarboxylic acid (TCA) cycle, in the reprogramming of macrophage function. Macrophages are immune cells that play a crucial role in the immune response and inflammation. Metabolic reprogramming refers to changes in cellular metabolism that occur in response to different stimuli and influence cellular functions.
The authors highlight itaconate as a key player in the metabolic reprogramming of macrophages. They discuss how itaconate is produced in response to immune activation and the regulatory mechanisms that control its synthesis. Furthermore, the article explores the impact of itaconate on various cellular processes, including inflammation, antimicrobial activity, and regulation of gene expression.
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x is the maximum population that a given area can support
Carrying capacity
Population growth
Limiting factor
Immigration rate
Answers
Answer:
aa22
Explanation:
yeah yeah y
During meiosis, chromosome pairs randomly line up along each side of the cell equator. This arrangement mixes up the chromosomal combinations, which _______.
helps ensure reproductive success.
helps maintain all the previous generation's characteristics.
helps create and maintain genetic diversity.
helps ensure an equal number of males and females in the next generation.
Answers
Answer: C is the answer
do some research about the topic
How many significant figures in 20.8cm?
Answers
Answer:
\(\Huge \boxed{3}\)
Explanation:
Significant figures include non-zero digits and in between zeros.
2 0 . 8
20.8 has 3 significant figures.
Answer:
\(\huge\boxed{3 \ significant \ figures}\)
Explanation:
There are 3 significant figures in
2 0 . 8
According to the rules of significant figures:
=> All non-zero digits are significant.
=> Zeroes that come between 2 non-zero digits are also significant.
So, 3 significant figures in the term 20.8 cm.