Select the post-translational modifications of histones that are most commonly associated with changes in transcription levels in eukaryotes.

a. acetylation and lipidation
b. methylation and acetylation
c. glycosylation and ubiquitination
d. methylation and carboxylation

Answers

Answer 1

Correct option  C - methylation as well as acetylation

A DNA molecule is acetylated when an acetyl group is added, and a DNA molecule is methylated when a methyl group is added.

It is generally known that both histone deacetylation and DNA methylation inhibit gene transcription. In contrast, when histones are deacetylated by HDAC, their electrostatic contacts with DNA become stronger, resulting in relaxed chromatin that upregulates transcription.

Histone acetylation and DNA methylation are examples of epigenetic changes. However, histone acetylation is a chemical covalent modification that occurs in proteins as a post-translational modification of histone proteins, whereas DNA methylation occurs at the DNA level.

Histone modification, which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation, is a covalent post-translational modification of histone proteins. These changes to chromatin structure can regulate gene expression.

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Related Questions

Explain the propagation of electrical impulses along a neuron including the role of myelin

Answers

Nerve impulses are signals that are transmitted along nerve fibers of the body.

Nerve impulses are electrical impulses. They are generated in response to stimuli.

These electrical impulses create:

action potentials as waves of depolarization that moves along the axons.

The axons contain voltage-gated ion channels that are either opened or closed by depolarization (which is the opening of ion channels leading to changes in membrane potential)

Depolarization further causes other channels to open and close thus spreading across the entire length of the axon and into another nerve cell (neuron).

Myelin sheaths act as buffers and through salt conduction help increase the speed of electrical impulses through the neurons. Not every nerve cell is insulated with a myelin sheath.

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hi i need help on this question real fast please help? 3 structures of water roots?

Answers

Answer:

Taproot. A root system which contains one large, primary vertical root that spawns many smaller horizontal root structures. ...

Fibrous. Fibrous root systems consist of many fine hairlike roots that form a thick mat below the surface. ...

Rhizomes. ...

Stolons. ...

Adventitious.

The picture below shows some features of the ocean floor. (1 point)

At which of these locations does the ocean floor spread apart to form new oceanic crusts?
Location A
Location B
Location C
Location D

The picture below shows some features of the ocean floor. (1 point)At which of these locations does the

Answers

Answer:

At D

it spreads at the mid ocean ridge ig

how do chemicals, hazardous wastes, oils, etc contribute to pollution and water quality?

Answers

Answer:

Hazardous, or toxic, waste is the potentially dangerous byproduct of a wide range of activities, including manufacturing, farming, water treatment systems, construction, automotive garages, laboratories, hospitals, and other industries. The waste may be liquid, solid, or sludge and contain chemicals, heavy metals, radiation, pathogens, or other materials. Even households generate hazardous waste, from items such as batteries, used computer equipment, and leftover paints or pesticides.

Toxic waste can harm people, animals, and plants, whether it ends up in the ground, in streams, or even in the air. Some toxins, such as mercury and lead, persist in the environment for many years and accumulate over time. Humans or wildlife often absorb these toxic substances when they eat fish or other prey.

In the past, many hazardous wastes were only loosely regulated, allowing substantial contamination of communities and the environment. In the U.S., toxic waste has been overseen by the federal Environmental Protection Agency (EPA) since 1976, as well as state departments of environmental protection. The EPA now requires that hazardous waste be handled with special precautions and be disposed of in designated facilities. Many towns have special collection days for household hazardous waste.

Help me out I’m stuck here

Help me out Im stuck here

Answers

Answer:

The cells survive best under acidic conditions

Explanation:

To understand this graph, you first need to understand what data is being given. All you are given is cell survival and pH.

With this, the pH has an obvious effect on cell survival. Higher pH (basic environment) correlates to more cells dying. Knowing this, you can rationalize that the more acidic environments with a low pH are the best environment for it.

Also, it would not survive well in distilled water since its pH lies somewhere north of 6, which is shown to not be ideal here.

A mutation occurs in the coding region of a gene with the following sequence AAGTGC. The translated sequence is Lysine (AAG), Cysteine (TGC). Give an example of the following types of mutation using AAGTGC as your normal sequence. Provide the translated sequence caused by the mutation. (Hint: You will need a codon table to translate the sequence)
(a) Synonymous mutation
(b) Non-synonymous missense mutation
(c) Non-synonymous nonsense mutation

Answers

(a) Synonymous mutation: AAGTGC is the normal sequence coding for Lysine (AAG) and Cysteine (TGC). A synonymous mutation occurs when a gene changes its nucleotide sequence but the amino acid sequence remains unchanged. An example of this type of mutation using AAGTGC is AAGTGT. The translated sequence would still be Lysine (AAG) and Cysteine (TGT). This is because TGT is a codon for Cysteine, so the amino acid sequence remains unchanged.

(b) Non-synonymous missense mutation: AAGTGC is the normal sequence coding for Lysine (AAG) and Cysteine (TGC). A non-synonymous missense mutation occurs when a gene changes its nucleotide sequence and the amino acid sequence is also changed. An example of this type of mutation using AAGTGC is AAGTGA. The translated sequence would be Lysine (AAG) and Glutamic acid (TGA). This is because TGA is a codon for Glutamic acid, so the amino acid sequence is changed from Cysteine to Glutamic acid.

(c) Non-synonymous nonsense mutation: AAGTGC is the normal sequence coding for Lysine (AAG) and Cysteine (TGC). A non-synonymous nonsense mutation occurs when a gene changes its nucleotide sequence and the amino acid sequence is changed to a stop codon. An example of this type of mutation using AAGTGC is AAGTAA. The translated sequence would be Lysine (AAG) and Stop codon (TAA). This is because TAA is a codon for Stop codon, so the amino acid sequence is changed from Cysteine to Stop codon, which causes the protein to be truncated.

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Molecules that can cross the cell membrane by simple diffusion are: Please choose the correct answer from the following choices, and then select the submit answer button. Answer choices large. ions. hydrophilic. uncharged.

Answers

Molecules that can cross the cell membrane by simple diffusion are C. uncharged molecules.

The cell membrane is composed of a phospholipid bilayer, which consists of two layers of phospholipid molecules. Phospholipids have a hydrophilic (water-loving) head and a hydrophobic (water-fearing) tail. This arrangement forms a barrier that separates the interior of the cell from its external environment.

Simple diffusion is a passive process where molecules move from an area of higher concentration to an area of lower concentration, driven by the concentration gradient. It occurs directly through the lipid bilayer without the need for energy or assistance from transport proteins.

For a molecule to passively diffuse through the cell membrane, it should meet certain criteria. These criteria include being small in size, nonpolar, and uncharged. Let's break down why these characteristics are important:

Small size: Small molecules can easily pass between the lipid molecules in the membrane. The smaller the molecule, the easier it can diffuse through the membrane.Nonpolar: The interior of the cell membrane is primarily composed of hydrophobic tails of phospholipids. Nonpolar molecules are soluble in lipids, making them capable of dissolving in the hydrophobic region of the membrane. This allows them to diffuse through the lipid bilayer.Uncharged: Charged molecules, such as ions, have difficulty crossing the lipid bilayer because they are repelled by the hydrophobic region of the membrane. Since simple diffusion does not involve transport proteins or channels, charged molecules cannot diffuse across the membrane through this process.

In contrast, ions, hydrophilic molecules (which are polar and attracted to water), and large molecules generally cannot cross the cell membrane by simple diffusion alone. These molecules require specialized transport mechanisms such as ion channels, carrier proteins, or active transport processes to facilitate their movement across the membrane.

Therefore, the correct answer is C. uncharged molecules, as they fulfill the necessary criteria to passively diffuse through the cell membrane via simple diffusion.

The correct question is:

Molecules that can cross the cell membrane by simple diffusion are ?

A. ions.

B. hydrophilic.

C. uncharged molecules.

D. large.

E. All molecules can cross the cell membrane by simple diffusion.

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how many glucose are made during the krebs cycle

Answers

The Krebs cycle does not produce glucose, but instead produces energy  from the breakdown of glucose.

How many glucose are made during the krebs cycle?

The Krebs cycle, also known as the citric acid cycle or the tricarboxylic acid (TCA) cycle, is a series of biochemical reactions that occur in the mitochondria of cells, and plays a central role in cellular respiration.

The Krebs cycle does not produce glucose, but rather it oxidizes acetyl-CoA, which is derived from the breakdown of glucose or fatty acids, and produces energy in the form of ATP.

During the Krebs cycle, one molecule of acetyl-CoA enters the cycle and undergoes a series of reactions.

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What are the 12 cranial nerves and their function?

Answers

Your 12 cranial nerves each have a specific function. Experts categorize the cranial nerves based on number and function:

Olfactory nerve: Sense of smell.
Optic nerve: Ability to see.
Oculomotor nerve: Ability to move and blink your eyes.
Trochlear nerve: Ability to move your eyes up and down or back and forth.
Trigeminal nerve: Sensations in your face and cheeks, taste and jaw movements.
Abducens nerve: Ability to move your eyes.
Facial nerve: Facial expressions and sense of taste.
Auditory/vestibular nerve: Sense of hearing and balance.
Glossopharyngeal nerve: Ability to taste and swallow.
Vagus nerve: Digestion and heart rate.
Accessory nerve (or spinal accessory nerve): Shoulder and neck muscle movement.
Hypoglossal nerve: Ability to move your tongue.

The 12 cranial nerves are: Olfactory nerve (I), Optic nerve (II), Oculomotor nerve (III), Trochlear nerve (IV), Trigeminal nerve (V), Abducens nerve (VI), Facial nerve (VII), Vestibulocochlear nerve (VIII), Glossopharyngeal nerve (IX), Vagus nerve (X), Accessory nerve (XI) and Hypoglossal nerve (XII).

What are the functions of cranial nerves l, ll and lll?

The function of the Olfactory nerve (I) is that it is responsible for the sense of smell. The optic nerve (II) is responsible for vision. Oculomotor nerve (III) controls eye movement and regulates the size of

the pupil.

Which cranial nerve is responsible for taste sensation and controlling the muscles?

The glossopharyngeal nerve (IX) is responsible for taste sensation in the back one-third of the tongue and controls swallowing and speech. Vagus nerve (X) is responsible for controlling the muscles of the larynx and pharynx, and for transmitting sensory information from the digestive system.

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You and your physiology instructor are trapped in an overturned ship. To escape, you must swim underwater a long distance. You tell your instructor it would be a good idea to hyperventilate before making the escape attempt. Your instructor calmly replies, "What good would that do, since your pulmonary capillaries are already 100% saturated with oxygen?" What would you do and why?

Answers

In this scenario, hyperventilation would be counterproductive as the pulmonary capillaries are already 100% saturated with oxygen.

Hyperventilation would actually decrease the amount of carbon dioxide in the blood, causing the blood pH to rise, leading to respiratory alkalosis and even unconsciousness. Therefore, the instructor is correct in advising against hyperventilation before attempting to swim underwater a long distance. Instead, it would be better to take a few deep breaths and then start swimming underwater.

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In the beginning of an experiment, there are 10 bacteria. Suppose the rate of growth is proportional to the number of bacteria. After one hour, the number of bacteria increase to 20. Suppose P(t) is the number of bacteria present at time t. Try to find P(t).

Answers

In this experiment, the rate of bacterial growth is proportional to the number of bacteria present. We can use this information to find an equation that describes the number of bacteria at any given time.

Let's start by assigning variables. Let P(t) represent the number of bacteria at time t. We know that at the beginning of the experiment, there are 10 bacteria, so we can write this as P(0) = 10.

We are given that after one hour, the number of into 20. This means that after one hour, P(1) = 20.
Since the rate of growth is proportional to the number of bacteria, we can write this relationship as a differential equation: dP/dt = kP, where k is the proportionality constant.

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Explain how to distinguish different species by their DNA.

Answers

DNA analysis can be used to distinguish different species by comparing specific regions of their DNA sequences.

To distinguish different species by their DNA, scientists primarily focus on comparing specific regions of the DNA sequences that are highly variable among species. One commonly used region is the mitochondrial DNA (mtDNA), which is inherited maternally and has a higher mutation rate compared to nuclear DNA. Another region is the ribosomal RNA genes (rRNA), which exhibit variations among species.

The process typically involves extracting DNA samples from different organisms, isolating the target region of interest, and sequencing the DNA to determine the nucleotide sequence. The sequences obtained from different species are then compared to identify differences and similarities.

These differences can be used to create DNA profiles or genetic markers specific to each species. Advanced techniques such as DNA barcoding or whole-genome sequencing can provide more comprehensive information and aid in species identification.

By comparing DNA sequences, scientists can uncover genetic variations unique to different species, allowing them to distinguish and classify organisms accurately. This information is valuable in various fields, including taxonomy, conservation biology, forensic science, and evolutionary research.

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how is global warming most significantly affecting coral reefs and sea life?

Answers

Thermal stress brought on by a warming ocean: promotes coral bleaching and infectious illness.

For reefs close to land-based sources of sediment, sea level rise may result in increased sedimentation. Coral may become suffocated by sediment discharge.Changes in storm patterns: result in storms that are stronger and more frequent and can destroy coral reefs.Changes in precipitation: Increasing freshwater flow, silt, and pollution from the land contribute to algae blooms and make the water murky, which cuts down on light.Changes in connectivity and temperature regimes brought on by altered ocean currents make it harder for coral larvae to spread out and add to the lack of food for corals.Ocean acidification, which is brought on by more CO2, lowers pH levels, which inhibits coral growth and structural integrity.

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9. Mammals have backbones. Which word in the list below is a synonym for backbones?
monotreme
vertebra
O endotherm
marsupial

Answers

Answer: Vertebrae

Explanation:

Brainly Est question

Absorbs water and nutrients into the plant.

A) Roots
B) Stem
C) Flower
D) Leaf

Answers

It’s the (A) - Root, because the roots are the main part of the plant that holds and absorbs the water in the plant. Hope this helped!

What ultra-stable molecule is split during PSII?

Answers

Sorry I don’t really know

approximately how long ago did plants evolve from green algae?

Answers

The emergence of plants from green algae occurred around 500 million years ago, during a period of significant diversification of life in the oceans known as the Ordovician period.

When did plants evolve from green algae?

Plants are believed to have evolved from green algae approximately 500 million years ago, during the Ordovician period of the Paleozoic era. This process of evolution involved various genetic, physiological, and morphological changes that allowed the ancestral algae to adapt to life on land, including the development of structures such as roots, stems, and leaves for support and nutrient uptake, as well as specialized reproductive structures.

The transition from aquatic to terrestrial habitats represented a major milestone in the history of life on Earth and paved the way for the subsequent diversification of plants and the evolution of complex ecosystems.

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the classification of an organism and the scientific name of an organism are different because ____.

Answers

The classification of an organism and the scientific name of an organism are different because the full classification of the organism basically include more categories of organisms as compared to their scientific names.

Full classification of an organism involves is all the different levels which are the kingdom, phylum, class, order, family, genus, as well as species.

A scientific name of a particular organism on the other hand contains information only about its genus as well as species. For example, Panthera tigris is the scientific name of a tiger and in this Panthera is the name of the genus and tigris is the name of the species.

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The majority of a cell's interior is made
up of...
O mitochondria
O cytoplasm
Onuclei (that's plural for nucleus)
Oribosomes

Answers

Answer:

Nucleus

Explanation:

rats that have a damaged _________ will show no fear when placed next to a cat.

Answers

Rats that have a damaged amygdala will show no fear when placed next to a cat.

The amygdala is a part of the brain that plays a crucial role in processing emotions, particularly fear and anxiety. It is involved in evaluating potential threats in the environment and initiating fear responses. Studies have shown that damage to the amygdala can lead to a significant reduction or complete absence of fear responses.

In the specific scenario mentioned, rats with a damaged amygdala would not exhibit the typical fear response when placed next to a cat, despite the cat being a natural predator.

This is because the amygdala is responsible for signaling danger and triggering fear-related behaviors, which would normally be evoked in the presence of a potential threat like a cat. Without an intact amygdala, the rats would not recognize the danger and thus display a lack of fear.

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compared with men, women produce more alcohol dehydrogenase enzyme in the stomach.

Answers

Men generally produce higher levels of alcohol dehydrogenase (ADH) enzyme in the stomach compared to women. This statement is false.

Alcohol dehydrogenase is an enzyme responsible for breaking down alcohol in the body. It helps convert ethanol into acetaldehyde, which is further metabolized into less toxic substances.

The presence of ADH in the stomach contributes to the initial breakdown of alcohol before it enters the bloodstream.

The difference in ADH activity between men and women is influenced by various factors, including genetics and hormonal differences. Men tend to have higher levels of ADH in the stomach, leading to a more efficient breakdown of alcohol at an early stage of digestion.

This can result in a faster metabolism of alcohol and potentially affect how men and women respond to alcohol consumption.

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What is the arrow pointing to?

hydrogen ion
water
hydroxide ion
proton
hydronium ion

What is the arrow pointing to?hydrogen ion water hydroxide ion proton hydronium ion

Answers

The arrow points to the hydroxide ion.

What is an ion?

An ion is a specie that is formed by the loss or gain of electrons. Thus any specie that carries a charge whether positive or negative could be called an ion. In this case, we have a system that has three ions in it. The hydrogen ions, the hydroxide ions and the hydronium ions.

As we can see, the red color stands for oxygen, the grey color stands for hydrogen. Looking at the image, we can see that the direction in which the arrow point is a specie that has only red and ash colors thus this corresponds to  the hydroxide ion.

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The structural layer of the earth that flows because it is hot and under extreme pressure is what?

The structural layer of the earth that flows because it is hot and under extreme pressure is what?

Answers

Answer is outer core.

Reason - The outer core is the third layer of the Earth. It is the only liquid layer. The outer core is responsible for Earth's magnetic field.

The Covid-19 pandemic has accelerated the adoption of remote work practices. It is highly likely that hybrid work models will become the norm at post-pandemic workplaces globally, as well as in South Africa. Hybrid work models would bring many challenges to both employees and managers in South Africa - a country also known for its diversity and inequalities.

QUESTION

Compare Maslow’s hierarchy of needs theory and Alderfer’s ERG theory by critically applying these two theories to the above scenario. Make reference to appropriate interventions by senior managers in motivating both frontline employees as well as middle managers.

Answers

Maslow's Hierarchy of Needs was transformed by Clayton Alderfer into the three-factor ERG model of motivation. According to Maslow's theory, people never reach a stable degree of need satisfaction.

In Alderfer's concept, the letters E, R, and G stand for existence, relatedness, and growth, respectively. A content theory of motivation is the ERG model. According to Alderfer's paradigm, these three demands are what drive all human motivation. Existence, which is the first of Alderfer's 3 necessities, is the most immediate and pressing necessity. It generally relates to both physical and psychological survival.

The need for a positive relationship with oneself, a sense of belonging, and relatedness has advanced. The least obvious but nevertheless important component of the ERG model is Alderfer's drive for growth, which is really tied to growth, happiness, and the experience of reaching one's potential.

Maslow's theory would imply that people should strive to meet their immediate needs while at work, and that managers and leaders should concentrate on assisting their teams in meeting one particular level of need at a time. Before going on to the next level of demands in Maslow's Hierarchy of demands, people must have satisfied the previous one. For instance, they must first have their demands for safety met before being driven by a sense of social connection.

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All of these are risks of renewable energy except
A. can disrupt migration patterns of birds
B. can cause flooding
C. can contaminate groundwater
D. can spill during transport and disrupt ecosystems​

Answers

Answer:

D. can spill during transport and disrupt ecosystems

Explanation:

The correct option would be "D. can spill during transport and disrupt ecosystems" as it is not a risk of renewable energy sources, as renewable energy sources such as solar, wind, and hydroelectric power do not involve transport of fuels and do not have the risk of spills.

How can chemical differentiation be used to explain the distribution of elements on Earth OR within our solar system?

Answers

Answer:

Substances in nature rarely exist as single element but combination of more than one elements.

This combination of element is referred to as compounds.

These compounds can breakdown from temperature change or change in pressure and so on ,these atmospheric change exist in nature and with long climatic change over a period and could lead to elements recombining and could be transported to other areas from weathering.

The molecule that functions as the reducing agent in a redox reaction ___ electrons and ______ energy.

Answers

The molecule that functions as the reducing agent in a redox reaction donates electrons and releases energy.

Two species—the oxidizing agent (or electron acceptor) and the reducing agent (or electron donor)—are engaged in a redox reaction (reduction-oxidation) . The species that loses electrons is the reducing agent, whereas the species that obtains electrons is the oxidizing agent.

The reducing agent gives electrons to the oxidizing agent during a redox reaction. As a result of losing electrons, the reducing agent itself undergoes oxidation. Electric current or energy transmission is made possible by this transfer of electrons from the reducing agent to the oxidizing agent.

The reducing agent releases energy while contributing electrons. The energy that is emitted can take on many different forms, including heat, light, or chemical energy. The change in the electrochemical potential energy of the electrons as they move from the reducing agent to the oxidizing agent is what causes this energy.

In general, the reducing agent works by giving electrons to the oxidizing agent while losing its own electrons in the process. This electron transfer causes the electrochemical potential energy to shift, releasing energy that can be used or seen as different types of energy.

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If there is 37% of cytosine in a molecule of double-stranded DNA, what percentage of guanine is present?
A.) 63%
B.) 40%
C.) 37%
D.) 60%

Answers

B would be the answer to your question

Answer: B

Explanation:

If you REALLY think about it , you will see that it is 40%

influenced by Darwin's ideas about evolution, Edward Tylor and Lewis Henry Morgan argued that human societies evolved through stages from:

Answers

I think the answer is
Savagery —> Barbarism —> Civilization

True/Falsedeep sea fans are deposited at the base of submarine canyons by turbidity currents. when preserved in the geologic record, these deposits are known as turbidites.

Answers

True, deep sea fans are deposited at the base of submarine canyons by turbidity currents. When preserved in the geologic record, these deposits are known as turbidites.

Deep-sea fans are underwater geological structures that form as a result of sediment deposits that are transported through turbidity currents from the continental shelf, slopes, and canyons to the deep ocean floor. These fans are found at the bottom of underwater canyons, deep-sea trenches, and abyssal plains.

Depositional environments that are turbidites Submarine canyons and deep-sea fans are examples of depositional environments for turbidites. When massive amounts of sediments are moved and accumulated by gravity from the upper to the lower parts of the continental slope, this results in a phenomenon known as turbidity currents.

The movement of turbidity currents is responsible for the transportation of the sediments and depositing them in different places. In deep-sea canyons, turbidites form as a result of a combination of fast-moving waters and steep walls that allow for the collection of sediments into the canyon's lowest regions. When turbidity currents deposit these sediments in the ocean, the resulting sedimentary deposits are known as turbidites.

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