outline an optimal treatment plan for julie and explain your reasoning. discuss the tradeoff s encountered during the composition of your plan (consider alternative drug targets and a bone marrow transplant).

Answers

Answer 1

The primary medication used to treat CML is a drug named imatinib. It is typically administered quickly after a cancer diagnosis in order to decrease the disease's course and keep it from progressing to an advanced stage.

Reduced formation of aberrant white blood cells is how imatinib functions.

BMT, commonly referred to as a bone marrow transplant as well as hematopoietic stem cell transplant could treat AML for patients of any age. It swaps out harmful stem cells with good blood-forming ones. Many people's diseases can be cured through transplants.

A bone marrow, meaning stem cell, transplant is such kind of therapy for CML where the patient receives transplanted bone marrow from a donor. The first and only recognized treatment that can completely cure CML would be an allogeneic transplant.

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Related Questions

Most fish deposit fertilized eggs, but some sharks keep the fertilized egg inside the female until she gives birth to a relatively well-developed pup. These sharks would thus be characterized as ________. viviparous ovoviviparous livebearing oviparous

Answers

Answer:

Explanation:

These sharks would thus be characterized as __ oviparous______.

what is photosynthesis?????​

Answers

Photosynthesis is a process used by green plants by which they produce Carbohydrates and Oxygen from water and carbon dioxide in presence of Sunlight

The chemical reaction is given by

\(\\ \sf\longmapsto CO_2+H_2O\overset{\sf Sunlight}{\longrightarrow}C_6H_{12}O_6\)

describe the process of digestion (20marks)​

Answers

Answer:

The processes of digestion include six activities: ingestion, propulsion, mechanical or physical digestion, chemical digestion, absorption, and defecation. The first of these processes, ingestion, refers to the entry of food into the alimentary canal through the mouth.

Accessory organs: Liver: produces bile salts

Small intestine: Mixes chyme with digestive juice

Stomach: Mixes and churns food with gastric juice

Mouth: Ingests food; Chews and mixes food

Explanation:

Extinctions that occur at a moderate rate and continuously open a limited number of opportunities for the origin of new species and new niches are known as __________ extinctions

Answers

Extinctions that occur at a moderate rate and open a limited number of opportunities for the origin of new species are known as background extinctions.

What are background extinctions?

Extinction is the physical disappearance of one given species and/or population in an ecosystem.

The term 'background extinctions' makes reference to the extinction that does not generate new niches in an ecosystem.

Background extinctions are well known because they do not contribute to the emergence of biodiversity.

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membrane bound structure in eukaryotic cells that
contains DNA

Answers

jwodkdjwjjwoeoejwjjejejeodowjhendd

1.) which enhancer region is hundreds to thousands of base pairs upstream or downstream of the transcription start site?

Answers

The enhancer region hundreds to thousands of base pairs upstream or downstream of the transcription start site is called the "enhancer region". This region consists of hundreds to thousands of bases upstream or downstream of the transcription start site and is responsible for modulating gene expression.

These elements are recognized by regulatory proteins that bind to specific SREs or TRs. These regulatory proteins act as activators or inhibitors of transcription. These enhancer regions can affect transcription at various distances, either directly (upstream) or indirectly (downstream).

In conclusion, enhancer regions are located hundreds or thousands of base pairs upstream or downstream of the transcription start site and contain transcriptional regulatory elements. These elements are recognized by regulatory proteins, which can activate or inhibit transcription.

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A (____) is a statement saying that what is presented is true.

Answers

Answer:

A ‘receipt’ is a statement saying that what is presented is true

Explanation:

Hope this helps!(づ ̄3 ̄)づ╭❤~

answer: a receipt is a statement saying that what is presented is true

Which statements describe homologous structures? Check all that apply. O An example of a homologous structure is the wing of a bird and an insect. An example of a homologous structure is the forelimb of a whale, a human, and a dog. Homologous structures have the same function but a different structure. O Homologous structures have the same structure, but may have a different function. O Homologous structures indicate a common ancestor. O Homologous structures do not indicate a common ancestor. Intro​

Answers

Answer:

Explanation:

whale, human, dog

have the same structure but different function

indicate a common ancestor

Answer:

the second one

the fourth one

the fifth one

Explanation:

i did it and its right

what process happens in the fluid filled space outside of the granum?

a) krebs cycle

b) calvin cycle

c) light dependent reactions

d) glycolysis

Answers

Answer:

Calvin cycle is your answer.

Explanation:

hope it helps you.

which of the following theories argues that education teaches socialization skills, shared culture, and the importance of civic engagement?

Answers

The theory that argues education teaches socialization skills, shared culture, and the importance of civic engagement is known as the Functionalist Theory of Education. This theory emphasizes the role of education in maintaining social order and transmitting values and norms within a society.

The Functionalist Theory of Education views education as a crucial institution that serves multiple functions in society. According to this theory, education plays a significant role in socializing individuals by teaching them the necessary skills and knowledge to function effectively within their community. This includes imparting socialization skills, such as communication, teamwork, and cooperation, which are essential for individuals to interact and work together harmoniously in society. Furthermore, education also transmits shared culture by providing individuals with a common set of values, beliefs, and knowledge that bind them together. Through formal and informal curriculum, individuals are exposed to cultural practices, traditions, and historical narratives that contribute to a sense of identity and belonging within a particular society. This shared culture helps foster social cohesion and a collective understanding of what it means to be a member of that society. Moreover, the Functionalist Theory of Education highlights the importance of civic engagement. Education is seen as a means to instill civic values, promote active citizenship, and prepare individuals to participate in the democratic processes of their society. It aims to develop responsible and informed citizens who can contribute positively to their communities through political participation, community service, and the understanding of civic rights and responsibilities. In summary, the Functionalist Theory of Education posits that education teaches socialization skills, shared culture, and the significance of civic engagement. It underscores education's role in maintaining social order, transmitting values, and preparing individuals to actively participate in their society.

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human immunodeficiency virus (hiv) is classified as an rna virus because its genome, or genetic material, consists of a single strand of rna.

Answers

It is true that human immunodeficiency virus (HIV) is classified as an RNA virus because its genome, or genetic material, consists of a single strand of RNA.

Because its genetic material is made up of a single strand of RNA (ribonucleic acid), the human immunodeficiency virus (HIV) is categorized as an RNA virus.

RNA viruses, unlike DNA viruses, contain RNA as their major genetic material rather than double-stranded DNA.

HIV is a kind of RNA virus that belongs to the retrovirus family. Retroviruses, such as HIV, are distinguished by the presence of an enzyme known as reverse transcriptase.

Once inside the host cell, this enzyme permits the virus to transform its RNA genome into DNA. The viral DNA is subsequently incorporated into the DNA of the host cell, allowing the virus to multiply and remain within the host.

Thus, the given statement is true.

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Your question seems incomplete, the probable complete question is:

State true or false:

human immunodeficiency virus (hiv) is classified as an rna virus because its genome, or genetic material, consists of a single strand of rna.

Black (B) is co-dominant to white (W). What percentage of the offspring will be black-and-white if a black cat is crossed with a white cat?

Answers

Answer:

100% of offspring will be black and white

Explanation:

BW = Black and white

Because 4 out of 4 offispring fom the punnett squares have the genotype of BW, 100% of the offspring will be black and white

Black (B) is co-dominant to white (W). What percentage of the offspring will be black-and-white if a

All offspring will be black and white. Since 100% of the progeny from the will be black and white due to the genotype of BW in 4 out of 4 offspring,

What is codominance?

When two alleles codominate, neither can hide the manifestation of the other allele. However, neither allele is recessive in codominance, and both alleles' phenotypes are manifested.

When two alleles codominate, neither can hide the manifestation of the other allele. Codominant alleles are those that have an independent impact.

Both phenotypes are partially prevalent in codominance. Codominance is best illustrated by if a black cat is crossed with a white cat, all offspring will be black and white.

Therefore, if a black cat is crossed with a white cat, all offspring will be black and white.

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at the bouri site in ethiopia, what possible evidence of tool use did paleoanthropologists find accompanying the fossils attributed to australopithecus garhi?

Answers

In the Awash River valley in the Afar region of Ethiopia, Bouri is the location of paleoanthropological digs. It is well known for its 2.5-million-year-old Australopithecus garhi bones.

Some of the oldest indications of stone tool use in the history of human evolution can be seen on animal bones discovered there that have cut markings. Approximately one million years old fossils may also be found in the Bouri site, including a well-preserved Homo erectus skull with a brain that is more than twice the size of A. garhi. Stone tools from the early Acheulean industry are widespread. The site's animal fossils provide evidence of an open grassland setting. Some of the earliest known stone tools and animal bones that have been cut and cracked apart using stone tools are linked to Australopithecus garhi fossils. Therefore, it's probable that this species was among the first to use stone tools and to devour enormous animals' meat and bone marrow.

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In your own words, explain the process of photosynthesis and the goal of photosynthesis.

Answers

The process of photosynthesis is when green plants and other living things transform light energy into chemical energy. The goal of photosynthesis is to convert Radnet energy from the sun to chemical energy for food.

Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encoded the enzyme malate dehydrogenase. The following numbers of genotypes were observed:Genotype NumberM1M1 20M1M2 45M2M2 42M1M3 4M2M3 8M3M3 6Total 125A) What is the observed frequency of each genotype?B) What is the observed frequency of each allele?C) Based on H-W equilibrium and the allele frequencies calculated on part a, what is the expected frequency of each genotype?D) What is the expected number of individuals of each genotype under H-W equilibrium?E) Perform a Chi-squared analyses to determine whether the observed genotype numbers are consistent with H-W equilibrium. (To determine the degrees of freedom, use the formula DF = # of genotypes – # of alleles).

Answers

The observed frequency of each genotype is as follows:

M1M1: 20/125 = 0.16

M1M2: 45/125 = 0.36

M2M2: 42/125 = 0.34

M1M3: 4/125 = 0.03

M2M3: 8/125 = 0.06

M3M3: 6/125 = 0.05

The observed frequency of each genotype is calculated by dividing the number of individuals with that genotype by the total number of individuals in the population. In this case, there were a total of 125 individuals in the population. The number of individuals with each genotype was given in the question.

For example, there were 20 individuals with the M1M1 genotype, so the observed frequency of that genotype is 20/125 = 0.16 or 16%. Similarly, there were 45 individuals with the M1M2 genotype, so the observed frequency of that genotype is 45/125 = 0.36 or 36%. By calculating the observed frequencies for each genotype, we can get a better understanding of the genetic makeup of the population.

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The complete question is:

Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encoded the enzyme malate dehydrogenase. The following numbers of genotypes were observed:Genotype NumberM1M1 20M1M2 45M2M2 42M1M3 4M2M3 8M3M3 6Total 125A) What is the observed frequency of each genotype?

How long did the cicadas in the video live underground?
O A. 17 days
O
B. 7 months
O
C. 7 years
O
D. 17 years

Answers

Answer:

D. 17 years

Explanation:

if you were in 2004 cicadas were around that time. 2004 to get to 2021 is 17 years so its D

hope this helped

An observation is _____.

A. A positive explanation for events using prior knowledge

B.Always quantitative

C. Made using any of the five sentences

D. Always qualitative

Answers

Answer:

A

Explanation:

none of the other answers make sense at all

Answer:

C. Made using any of five sentences

Explanation:

The graph represents changes to two jackrabbit populations in two different areas over 15 years.
a. Which of these populations experienced the faster growth rate over the first five years? Explain your answer.
b. Which of these populations probably experienced more births than deaths over the first five years?
c. What is the approximate carrying capacity for each population, as indicated by the graph?
d. At carrying capacity, how would the growth rate of the population in area A compare with the growth rate of the population in area B?
e. Although the two populations started out at the same size, one population grew larger than the other. What are two environmental factors that could have limited the growth of one of these populations?
f. For the population in area A, which part of the chart shows exponential growth and which shows logistic growth?
g. What are two possible changes to environmental factors that could cause the population in area B to experience positive population growth that would allow it to reach the same carrying capacity as the population in area A?

The graph represents changes to two jackrabbit populations in two different areas over 15 years. a. Which

Answers

Answer:

B: blue experienced more death than red

Sam and his Dad were trying to combat the fire ants in the backyard. They tried several brands of fire ant "killing" chemicals but none worked. Finally, Sam's Dad decided to try an old-time idea: pouring grits on the mounds.

What question could be used to guide Sam's study of fire ants?
A) Why is it so difficult to kill fire ants?
B) If grits are poured in a fire ant mound, then the ants will die.
C) Do grits work better at killing fire ants than commercial products?
D) Will ants eat grits and die when grits are poured in a fire ant mound?

Answers

Answer: Tbh i dont rlly know But i think it might be C. do grits work better at illing ants than commercial products?

If im wrong srry!

Hope this helps!

Explanation:

___Ca + ___CuF2---->____ CaF2 + Cu

help me solve the chemical equation ​

Answers

Answer:

?? i need help to??????????? help me

Photosynthesis is the process through which an organism internally makes food by breaking down sunlight. Organisms that make food through photosynthesis are classified as "autotrophs," as opposed to "heterotrophs," which must consume other organisms to make their food. (SC. 912. L. 15. 6)


Which three kingdoms have organisms that can photosynthesize?

Answers

Three kingdoms that have organisms capable of photosynthesis are:

PlantaeProtistaBacteria

Plantae: Plants are the fundamental organisms involved in photosynthesis. Plants have developed specialized structures and adaptations to capture sunlight and perform the photosynthetic process. The capacity to transform sunlight into energy distinguishes plants from autotrophs.Protista: Within the Protista kingdom, an alga is a group of organisms that are capable of photosynthesis. Algae come in a variety of shapes and sizes, ranging from unicellular organisms to multicellular organisms. Algae can be found in both freshwater and marine ecosystems.Bacteria: Bacteria are generally heterotrophic organisms, however, some species within the Kingdom of Bacteria have evolved the capacity to generate energy through photosynthesis. For example, cyanobacteria are characterized by their ability to generate energy from sunlight, and they inhabit a variety of aquatic and terrestrial environments.

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watson and crick built models that demonstrates that____

Answers

Watson and crick built models that demonstrates that____DNA is made of two chains in a double helix.

What is Deoxyribonucleic acid?

Deoxyribonucleic acid is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

There are four types of DNA such as :

Replication. DNA exists in a double-helical arrangement in which each base along one strand binds to a complementary base on the other strand.Encoding InformationMutation and RecombinationGene Expression

Therefore, DNA is a complex  long-chained molecule that contains the genetic blueprint for building and maintaining all living organisms.

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Which organelle is responsible for making lipid molecules that will be used by the cell?

Smooth ER

Nucleus

Lysosome

Rough ER

Answers

The endoplasmic reticulum (ER) is a series of interconnected membranous sacs and tubules that collectively modifies proteins and synthesizes lipids. However, these two functions are performed in separate areas of the ER: the rough ER and the smooth ER.

what is difference between self pollination and cross pollination? Help me​

Answers

Answer:

Cross-pollination is the transfer of pollen from the anther of one flower to the stigma of another flower on a different individual of the same species. Self-pollination occurs in flowers where the stamen and carpel mature at the same time, and are positioned so that the pollen can land on the flower's stigma.

A Subway customer removed the following items from his sandwich: ham and turkey, oil and vinegar,
wheat bread. Construct a written argument in paragraph form that addresses the following:
• Which macromolecule category does each food item belong to?
● What monomer unit must each food item be broken down into to perform cellular processes?
What cellular processes could potentially be impacted if the customer's daily diet consists of
eliminating these macromolecules? (Describe 3 processes)

Answers

Ham and turkey belong to the macromolecules of proteins, oil and vinegar belong to the macromolecules of fats and oil, while wheat bread belong to the macromolecules of carbohydrates.

What are macromolecule nutrients?

The macromolecule nutrients are those nutrients that are made up of large organic molecules which are usually proteins, carbohydrates, fats and oil.

The macromolecule category that each food item belong to include the following:

Ham and turkey belong to the macromolecules of proteins,

oil and vinegar belong to the macromolecules of fats and oil,

while wheat bread belong to the macromolecules of carbohydrates.

The monomer unit that each food item must be broken down into to perform cellular processes include the following:

Ham and turkey: must be broken down into amino acids.

Oil and vinegar: must be broken down to triglycerides.

Wheat bread: Must be broken down to glucose.

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In a marine ecosystem, producers __________. a. synthesize food from components of the abiotic environment b. eat consumers c. extract their energy from the water d. never decompose e. are an important source of carbon dioxide

Answers

Answer:

a. Synthesize food from components of the abiotic environment

Explanation:

Producers are organisms which typically obtain energy via the sun, an abiotic factor, so b. is incorrect (those that eat other consumers are called consumers). This suggests that producers are plants, which don’t produce carbon dioxide (e. is incorrect), can decompose (virtually all things that die can decompose so d. is incorrect), and don’t extract energy from water (yes, photosynthesis requires water, but it is not the sole substance use to generate energy for plants; thus, c. is incorrect).

Answer: a. option is correct synthesize food from components of the abiotic environment

Explanation: Marine ecosystem are the type of ecosystem exists in water. it has high levels of dissolved salt also covers most of the area on earth.

Producers in an ecosystem means the organisms which can make their own food. In marine ecosystem, some of the examples of producers are Red algae, Green algae, Daitoms etc. Producers performs a process in which they make their food and gain energy from the abiotic environment.

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What is the Family an d Species of Red Algae?
What is the species of Cyanobacteria?
(KPCOFGS)

Answers

The family of red algae is diverse and includes several different families, such as Rhodomelaceae, Gelidiaceae, and Porphyridiaceae.

The species of red algae vary greatly within these families. Cyanobacteria, on the other hand, belong to the phylum Cyanobacteria and are not classified using the KPCOFGS taxonomy system. Instead, they are classified based on their morphological and physiological characteristics.

Red algae, also known as Rhodophyta, comprise a large and diverse group of algae. They are classified into different families based on their characteristics, including the structure of their thallus (body), reproductive structures, and pigments. Some common families of red algae include Rhodomelaceae, Gelidiaceae, and Porphyridiaceae.

Within these families, there are numerous species of red algae, each with its unique characteristics and habitats. Cyanobacteria, also known as blue-green algae, are a group of photosynthetic bacteria. They belong to the phylum Cyanobacteria and are not classified using the KPCOFGS taxonomy system typically used for plants and animals.

Cyanobacteria are classified based on their morphological features, such as cell shape, arrangement, and pigmentation, as well as their physiological characteristics and genetic traits. The classification of cyanobacteria is continually evolving as new information and techniques are discovered in the field of microbiology.

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Where do chromosomal mutations begin?
Why do chromosomal mutations occur?

Answers

Answer:

A chromosome mutation is an unpredictable change that occurs in a chromosome. These changes are most often brought on by problems that occur during meiosis (division process of gametes) or by mutagens (chemicals, radiation, etc.).

Explanation:

Brainliest please?

Answer:

1) Different types of chromosome mutations can originate in the germinal cells.

2) Chromosome mutations are alterations occurring in chromosomes that typically result from errors during nuclear division or from mutagens. ... Abnormal chromosome numbers result from nondisjunction, or the failure of chromosomes to separate correctly during cell division.

Explanation:

This is what i found on the internet :/

a wholesale bakery would normally recognize revenue when

Answers

a wholesale bakery would normally recognize revenue when goods are delivered to the customer.

What is revenue?

The entire money derived from the sale of products or services pertaining to a business's core operations is referred to as revenue. Since it appears at the top of the income statement, revenue, also known as gross sales, is sometimes referred to as the "top line." An organization's whole profits or profit is known as income or net income.

The term "revenue" describes the entire profits a business makes through its primary activities, such as the sale of goods or services, the rental of real estate, regular payments, the interest on loans, etc.

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Why is it important for scientists to perform repeated experiments
A. So they can have preferences
B. So they can earn more money
C. So they can have less bias
D. So they can be less objective

Answers

Answer:

I think it is probably A

Explanation:

tell me I'm wrong in the comments

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