A genetic ailment called Tay-Sachs is passed from one generation of parents to the next. When a child inherits a defect (mutation) in the HEXA gene from both parents, the condition takes place.
Why does Tay-Sachs illness occur?An enzyme known as B-Hexosaminidase A (HexA) is required for the regular breakdown of a fatty substance known as GM2 ganglioside by the neurons of the nervous system, including the brain and spinal cord. The gene that instructs the neurons to create HexA is mutated in TSD patients, preventing the neurons from manufacturing the enzyme. In other words, the fatty substance accumulates in the brain and spinal cord, resulting in cell death and injury. A child must have an altered gene copy from both parents in order to have TSD. This implies that for a kid to have TSD, both parents must be hereditary carriers.
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Scott and Mary have accepted a three-year international relocation for work. Both are still paid in U.S. dollars, and their paychecks are automatically deposited to a U.S. Bank. When they need cash, they use local ATMs that allow them to withdraw funds from their U.S. bank, but the ATM gives them the equivalent in local currency. Which type of system does the U.S. Bank use to transfer money almost instantly, and in the currency needed by the user?
Answer:
The answer is "Electronic Funds Transfer".
Explanation:
It is a financial exchange electronically, which is also known as direct deposit salary services with ATM, which Cash subsidies among buyer marketing authorization, which implies digitally moving funds from one bank to the next. It's accomplices through the exchange of paper currency or certificates. The bank account is among the most popular applications of EFT.
Workplace diversity describes differences among workers in any of the following areas:
attitude
education
ethnicity
industry
Answer:
industry because here based the all the business in whole world
1. Describe how an apoptosis-inducing signal can transduce through intrinsic and extrinsic pathways to activate the initiator caspases. (10 marks)
Answer:
Explanation:
Apoptosis is an important biological process that regulates cell death and is essential for development, tissue homeostasis, and immune defense. Apoptosis-inducing signals can be transduced through intrinsic and extrinsic pathways to activate the initiator caspases.
The intrinsic pathway is initiated by cellular stress, such as DNA damage, hypoxia, or oxidative stress. These stress signals can activate the tumor suppressor p53, which in turn induces the expression of pro-apoptotic proteins such as Bax, Bak, and Puma. These proteins induce the release of cytochrome c from the mitochondria, which binds to Apaf-1 to form the apoptosome complex. The apoptosome complex recruits and activates initiator caspase-9, which then cleaves and activates the effector caspases-3, 6, and 7. This results in the cleavage of various cellular substrates, leading to the characteristic morphological and biochemical changes seen in apoptosis.
The extrinsic pathway, on the other hand, is initiated by extracellular signals such as cytokines, death ligands, or immune receptors. These signals bind to their respective receptors on the cell surface, which then activate caspase-8 through the recruitment of adaptor proteins such as FADD. Caspase-8 can also directly cleave and activate the effector caspases, leading to apoptosis. In some cases, the extrinsic pathway can also activate the intrinsic pathway through the cleavage of the pro-apoptotic protein Bid, which then translocates to the mitochondria and induces cytochrome c release.
In summary, apoptosis-inducing signals can transduce through both intrinsic and extrinsic pathways to ultimately activate the initiator caspases. These pathways intersect at various points and can crosstalk, leading to a coordinated and regulated cell death process.
Jason is an ancient history lover. He wants to share his knowledge on social media, but he does not think that video platform will work well since he cannot afford to travel to many of the places that have the ruins he wants to share information about. What would be the best social media platform to provide information show pictures of these places?
The best social media platform where Jason can share his knowledge and provide information and show pictures of these places is where common people and his friends near and all over can connect with him and can be friends with him on that networking site.
What is social media?Social media refers to the means of interactions among people in which they create, share, and/or exchange information and ideas in virtual communities and networks. We offer an array of tools, including one-on-one consults with schools, departments and offices looking to form or maintain an existing social media presence to discuss social media goals and strategy, as well as offer insights and ideas.
Before creating any social media account, we must submit the Account Request Form.
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what are the disadvantages of alloys
13. Suppose that expected inflation rises from 3% to 6%.
a. How will the real interest rate be affected by this
change?
b. How will the nominal interest rate be affected by this
change?
c. What will happen to the equilibrium quantity of
loanable funds
The equilibrium amount of funds that can be loaned will remain the same, while the nominal interest rate will rise by 3%.
How Does Inflation Work?The term "inflation" refers to a gradual decline in a person's ability to purchase goods and services. The average price increase of a selected basket of goods and services over some time can show the rate at which purchasing power decreases. As a result of the price increase, which is frequently expressed as a percentage, a unit of currency effectively costs less to buy than it did in previous times. Deflation, on the other hand, occurs when prices rise while purchasing power decreases. Even though it is simple to track how prices have changed over time for individual products, human needs go beyond just a few products.
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Macroeconomics is the branch of economics that focuses on:
A. comparing the lifestyles of poor and wealthy citizens.
B. economic principles affecting entire countries.
C. helping people find jobs when they're unemployed.
D. financial problems affecting individual families.
Answer:
B. economic principles affecting entire countries.
Explanation:
Macroeconomics is the part of economic studies that studies the economy of a country as a whole. In this branch of economics, the aggregate income, growth, expenditure and inflation are considered. The performance of the entire economy is measured under macroeconomics. National income, Gross domestic product, inflation and unemployment fall under the macroeconomic studies.
Answer:
economic principles affecting entire countries
Explanation:
i took the test
disclosing confidential information of a past employer to gain advantage at a new job is a violation of the standard of ethics?
Disclosing confidential information of a past employer to gain an advantage at a new job is a violation of the confidentiality standard of ethics.
What is ethics?Ethics or moral philosophy is a branch of philosophy that "involves systematizing, defending, and recommending concepts of right and wrong behavior". The field of ethics, like aesthetics, is concerned with matters of value; together, these fields comprise the branch of philosophy known as axiology.
Furthermore, ethics investigates the rational basis for our moral judgments; it investigates what is morally right or wrong, just or unjust. In a broader sense, ethics considers human beings and their interactions with nature and other humans, as well as freedom, responsibility, and justice.
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Generally, it is a sound business practice to take advantage of cash discounts. the money saved by paying invoices promptly is free to be used elsewhere. conversely, there is an implicit (opportunity) cost of foregoing a cash discount. by forgoing a cash discount, the small business owner is, in effect, paying an annual interest rate to retain the use of the discounted amount for the remainder of the credit period.
For example, assume that Jill anticipates she will receive invoices for $500 from the vendors offering cash discounts of 3/10, net 45.
a) how much will Jill save by paying within the discount period?
b) what will it cost Jill to retain the use of credit for 45 days?
c) what is the annual interest rate of the "loan" (ie. what is the annual rate of 3/10, net 45)?
Answer: a. $485
b. $15
c. 32.28%
Explanation:
a. how much will Jill save by paying within the discount period?
3% × $500 = 3/100 × $500 = 0.03 × $500 = $15
The amount saved will be:
= $500 - $15.
= $485
b) what will it cost Jill to retain the use of credit for 45 days?
This will be:
= 3% × $500
= 3/100 × $500
= 0.03 × $500
= $15
c) what is the annual interest rate of the "loan" (ie. what is the annual rate of 3/10, net 45)?
c) The annual interest will be calculated using:
= P x R x T
where,
I = interest = $15
P = principal = $485
R= rate of interest = Unknown
T= time factor = 15/365 = 0.0958
Then, annual Interest rate will be:
R = 15/ (485 x 0.0958)
R = 32.28%
Annual Interest rate is 32.28%
what is the difference between an 'increase in supply' and an 'increase in quantity supplied'?a. There is no difference between the two terms; they both refer to a movement along a given supply curve. b. There is no difference between the two terms; they both refer to a shift of the supply curve.c. An "increase in supply" means the supply curve has shifted to the right while an "increase in quantity supplied" means at any given price supply has increased. d. An "increase in supply" means the supply curve has shifted to the right while an "increase in quantity supplied" refers to a movement along a given supply curve in response to an increase in price.
Answer:
The correct answer is C. An "increase in supply" means the supply curve has shifted to the right while an "increase in quantity supplied" means at any given price supply has increased.
The difference between an 'increase in supply' and an 'increase in quantity supplied' are is no difference between the two terms; they both refer to a movement along a given supply curve. Thus, option (a) is correct.
What is supply?The term supply refers to the supply chain on the product or commodities. The supply was the manufacturer to vendor to wholesales to retailer to customer. The supply was an important part of the economic. The supply was the increases the price is low, The supply was low, the price was high.
According to the difference between on 'increase in supply' and an 'increase in quantity supplied' the both are the two terms on the supply curve. The supply curve as responsible to change the price.
As a result, the significance of the 'increase in supply' and an 'increase in quantity supplied' are the aforementioned. Therefore, option (a) is correct.
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Why is workplace diversity important for the success of the company?
A diverse workforce is more likely to understand your customers' needs and come up with ideas to fulfill them. Diversity in the workplace will also increase employee morale and instill a desire to be more effective and work more efficiently. This will greatly increase the productivity of your business.
sue, a single taxpayer, purchased a principal residence in 2009 for $415,000. in 2012, she paid $18,000 to add a sunroom. this year, sue sold the residence for $686,000. her selling expenses were $5,000. how much gain must sue recognize on the sale? multiple choice $25,000 $0 $16,000 $3,000
The term "cost price" refers to the amount paid for an item or its manufacturing cost. The abbreviation for the cost price is C.P. Selling Price: The term "selling price" refers to the price at which an item is purchased. The abbreviation for the selling price is S.P.
What is a selling cost?The purchase price of a product or service is known as the selling price. It can change based on how much buyers are willing to pay, how much the seller is willing to take, and how competitive the price is with other businesses in the market.
Gain on Sale of Residence Gain Selling Price - Selling Expenses - Cost Basis 686000-5000-433000 $248,000.00 Cost Basis Cost + Improvements 415000+18000 $433,000.00 Now we will talk about the gain that needs to be recognized.
The gain from the sale of the primary residence up to a maximum of $250,000 is exempt from income, according to IRS publication 523. Additionally, Julia has been in charge of the house for more than 24 months. In the given scenario, the gain is $248,000, which is less than the $250,000 threshold. As a result, no gain is included.
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I want to know about the difference between manufacturing business and service providing businees?plz.
briefly
Manufacturing businesses sell a different product than service businesses do. A manufacturing business creates and sells a physical product where a service business sells a service. For instance, a soap company is a manufacturing business. In contrast, a service business could be an accounting or a legal firm. In both cases, an action is for hire. The accountant will do taxes or the lawyer will prepare a brief. There is no physical product to sell; instead, the customer requires the service provider's involvement.
Explanation:Businesses tend to take one of two forms – manufacturing or service-oriented. As the names suggest, manufacturing businesses manufacture something where service businesses offer a service. Certainly, there are some businesses that do a little of both, like selling a product but also providing repair and leasing services. However, there are important differences between these business types, differences that span from the product sold to the way the company keeps its books.
Your project team has expressed their communal position that they would prefer not to have a review meeting at the end of the project. As project manager, how should you respond to show the value of this meeting?
How you respond should show the value of this meeting is: To tell the team that lessons learnt from the project process can be used in other projects.
A project manager is a person whose sole responsibility is to:
Plan the projectDirect the projectManage the projectMonitor the projectExecute the project etcSince the team said they would not have a review meeting at the end of the completion of the project the best decision as a project manager is to tell the team member that lessons learnt from the project process can be used in other projects since the project is a special or unique project.
Inconclusion the project manager should tell the team that lessons learnt from the project process can be used in other projects.
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My response to the expressed communal position of the project team's preference of not holding project review meetings is to stress its importance with regard to lessons for future projects.
The lessons that come from review meetings help the team to correct mistakes, realign processes, and improve performance.
Thus, since review meetings help to re-enforce the team's learning, I will reassure the team that the meeting would not take more time than necessary. I will also ensure that each team member participate actively.
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For a monopolist that does not price discriminate, economic profit is maximized in the short run at a price of $140. Marginal revenue at that output level is Group of answer choices equal to $140. greater than $140. less than $140. less than marginal cost. greater than average revenue.
what is a compounding period?
Answer:
Compounding periods are the time intervals between when interest is added to the account.
Explanation:
Interest can be compounded annually, semi-annually, quarterly, monthly, daily, continuously, or on any other basis.
How is a debit card different from a credit card?
A. A debit card is usually issued by a financial institution.
B. A debit card provides a way for people to make large purchases.
C. Spending on a debit card is limited to the funds available in an
account.
D. Spending can occur via a digital payment method.
Answer:
C
Explanation:
because thats wat ist is.- limited funds
application generation facilities are most often used by what group of employees?
Application generation facilities are typically used by technical or developer employees who are responsible for creating and maintaining software applications.
These facilities allow developers to quickly and easily generate custom applications based on predefined templates or standards, which can save time and effort compared to manually coding an application from scratch. Technical employees who use application generation facilities may include software developers, system administrators, or IT professionals who are responsible for maintaining and updating software applications.
With application generation facilities, developers can generate a custom application in a matter of minutes or hours, rather than the weeks or months it might take to manually code an application from scratch. This can save time and effort for developers, allowing them to focus on other tasks or projects.
Application generation facilities can be used to create a wide range of applications, including web applications, mobile applications, and desktop applications. They can be used by technical employees in a variety of industries, including software development, healthcare, finance, and manufacturing. Overall, application generation facilities are a valuable tool for technical employees who need to quickly and easily create custom software applications.
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what do chapter competitions entail?
Answer:
Whoever reads the chapter of the book the fastest is crowned the chapter king. It can be very competitive, and the competitors have to be very good readers.
Answer:
In FBLA you pick a subject and you either take a test, do a presentation, do sales pitch, etc. With reading, you read a chapter from a book as fast as you can.
Explanation:
Teams have better communication than other workers because they get to
a. Know each other better
b. Attend commurication seminars
C. Earn extra benetits packages
d. Use better telephones
Navel County Choppers, Inc., is experiencing rapid growth. The company expects dividends to grow at 19 percent per year for the next 8 years before leveling off at 5 percent into perpetuity. The required return on the company’s stock is 10 percent. If the dividend per share just paid was $1.52, what is the stock price?
Answer:
Price of stock = $74.636
Explanation:
The Dividend Valuation Model is a technique used to value the worth of an asset. According to this model, the worth of an asset is the sum of the present values of its future cash flows discounted at the required rate of return.
The price of the stock will the sum of the present value of the growing annuity and the growing perpetuity
Present value of dividend from year 1 to 8
The PV of the growing annuity = A/r-g) ( 1- (1+g)/(1+r)^n )
A- dividend payable now , r- required of return, g-growth rate, number of years
PV = 1.52×(1.19)/(0.1-0.19) × (1 -(1.19/1.1)^8)= 17.605
PV of Dividend from year 9 and beyond:
P = D× g/(r-g)
This will be done in two steps:
Step 1: PV(in year 8)of dividend = (1.52× 1.19^8× 1.05)/(0.1-0.05)= 122.250
Step 2 : PV in year 0 = 122.25× 1.1^(-8)= 57.030
Price of stock = 17.60 + 57.030= 74.63
Price of stock = $74.636
how does marmite use product differentiation
Marmite use product differentiation as viewed as having unique features, such as Marmite or the iPhone. It frequently referred to as a differentiator.
What do you mean by the product differentiation?
The feature or features that set your product or service apart from the competition for your target market are known as product differentiation.
It improves brand loyalty, sales, and growth by highlighting the differences between what you sell and what your rivals provide. These comprise vertical differentiation, mixed differentiation, and horizontal differentiation.
In the financial situation of today, product differentiation is crucial. It enables the seller to highlight the distinctive qualities that make their product outstanding by drawing comparisons between their own product and those of the market's rival products.
Therefore, Marmite use product differentiation as viewed as having unique features, such as Marmite or the iPhone. It frequently referred to as a differentiator.
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highlight characteristics of itinerant traders
what is business?????????????
A business is defined as an organisation or enterprising entity engaged in commercial, industrial,or professional activities.
List five internal factors that influence a sales forecast.
Answer:
The internal factors such as plant capacity, quality, price, advertisement policy, resources, etc., of the enterprise affect the sales forecasting of the enterprise.
Explanation:
These factors can very well be controlled by the business enterprise itself.
Question 9 of 10
Which of the following is not a suspicious email characteristic?
Offers that seem too good to be true
Emails claiming to be from government offices
Threatening emails or emails that appeal to sympathy
Spelling and grammar mistakes
Offers that seem too good to be true is not a suspicious email characteristic
What is a suspicious emailThe correct answer is "Offers that seem too good to be true" because while it is a common tactic used in phishing scams, it is not necessarily always a suspicious email characteristic. Other suspicious email characteristics include requests for personal information, unsolicited emails, emails that appear to be from a government office or financial institution, and emails that contain spelling or grammar mistakes.
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please help me, will give brainliest
The blanks in the financial statement can be filled such that :
FCFO = ( $ 30)FCFI = $ 63FCFF = $ 85Total FCF = $ 118How to find the FCFO, FCFI and FCFF ?FCFO, FCFI, and FCFF are all financial metrics used to evaluate the financial performance and cash flow of a company. They represent different types of free cash flow, which is the cash that a company generates from its operations after accounting for capital expenditures.
FCFO :
= -70 + 40
= - $ 30
FCFI :
= 150 - 87
= $ 63
FCFF :
= 80 - 44 + 200 - 54 - 97
= $ 85
The total FCF :
= 63 + 85 - 30
= $ 118
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Carradine Company prepares an adjusting journal entry to accrue salaries at year-end. What effect will this entry have on the financial statements
Answer: Increase in Liabilities; Decrease in Equity
Explanation:
If Salaries are accrued at year end, the salary expense will be credited to the Salaries Payable account which is a liability account to reflect that the company owes its staff some money.
The amount owed will be debited to the salaries expense account and so will reflect in the Income statement where it will reduce the net income for the period. This means that it will reduce Retained Earnings for the period and as Retained earnings is an Equity account, Equity in total will decrease.
China will be driving almost half of this growing market (48%) in 2025, but more,
importantly, with the increased use of batteries, what other service will see a global rise in
demand? As a result of this, what else will be opened, creating jobs?
multi-million ilkmlkkkjjhgdsimmm
merck spent more than ____ million on advertising and promoting the drug’s benefits
Merck spent more than $100 million on advertising and promoting the drug's benefits.
Merck, a drug company, invested more than $100 million in advertisements to promote their product, Vioxx, which was used to relieve pain from arthritis. Between 1999 and 2003, Vioxx became one of the most popular arthritis drugs on the market, with billions of dollars in sales.
However, the drug was linked to an increased risk of heart attacks and strokes, resulting in its removal from the market in 2004.The advertisements produced by Merck highlighted the drug's positive aspects, such as its ability to relieve pain and inflammation associated with arthritis, without mentioning the potential side effects, such as cardiovascular complications.
As a result of this omission, the drug's potential hazards were downplayed, putting people who took the drug at risk of severe health problems.Vioxx's withdrawal from the market has led to litigation against Merck, as the company faces thousands of lawsuits over the drug's safety concerns.
The case highlights the need for pharmaceutical companies to be transparent in their advertising and to prioritize consumer health over profits. In conclusion, Merck's investment in Vioxx's advertising and promotion, while it made the drug widely recognized, resulted in serious health hazards.
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