Describe how microarrays have led to improved diagnosis of two types of diffuse large b-cell lymphomas.

Answers

Answer 1

Diagnostic DNA microarrays have been utilised for genotyping, identification of disease-relevant genes or agents causing disorders, mutation analysis, SNP screening, chromosome abnormality detection, and global posttranslational modification determination.

What is Microarray test ?

In order to analyse the data generated from studies on DNA, RNA, and protein microarrays, which enable researchers to examine the expression state of a significant number of genes in many cases, an organism's whole genome in a single experiment, microarray analysis techniques are used.

Testing using chromosomal microarrays (CMA), also known as copy number variations, looks for additional (duplicated) or missing (deleted) chromosomal segments (CNVs).

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Related Questions

This questions has two parts
35 points

This questions has two parts 35 points

Answers

Part A

Answer: (A) Candida Albicans and Saccharomyces Cerevisiae

Explanation: They have the smallest difference in Cytochrome C

Part B

Answer: (B) The two species have high molecular homology

Explanation: Molecular homology means resemblances between species on the molecular level. Since the two species from the answer in Part A have the smallest difference in Cytochrome C it means they have high molecular similarities; this is due to evolving from the same common ancestor.

(A) is not the right answer because the fungi in the table might all look similar but have different or similar genetic blueprints.(C) is not the right answer because fungi can reproduce sexually or asexually, so reproduction cannot help with determining relatedness.(D) is not the right answer because if the two species from the answer in Part A are closely related because they are both fungi, the answer for Part A should be all of the options.

i need help please. my grades are going downhill please help by

i need help please. my grades are going downhill please help by

Answers

Answer:

see below

Explanation:

control variable- what is staying the same

dependent variable- what you are measuring

independent variable- what is changing

same motor- control

increase in voltage- independent

how fast electric motor turns- dependant

Hope this helps!

1) What is the monomer (building block) of a protein?

Amino Acids
Nucleotides
Legos​

Answers

Answer:

Amino acids

Explanation:

Amino acids are the building blocks of a protein

if, on average, 46% of the loci in a species' gene pool are heterozygous, then the average homozygosity of the species should be

Answers

According to the claim made, the species' average homozygosity should be 54%.

What does being a heterozygous mean?

(HEH-teh-roh-ZY-gus JEE-noh-tipe) a gene region in which there are two distinct alleles present. One normal gene and one mutated allele, or two distinct mutated alleles, can help compensate a heterozygous genotype (compound heterozygote).

What is heterozygous example?

You have a genetic trait for that gene if the two options differ from one another. For example, having one gene for red hair one and allele for brown hair could suggest that you are heterozygous for hair color. What traits are expressed depends on how well the two alleles are related.

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Use the drop-down menus to complete the hypothesis of the first group of researchers. During a drought, the decrease in rainfall will reduce the amount of vegetation that can grow and increase the occurrence of natural fires, so an elevation in Select… and a reduction in Select… should be found in the cores.

Answers

Answer:

Microscopic charcoal, Vegetation.

Explanation:

As the researchers conducting research in the Nile region identified that an increase in temperatures leads to an increase in droughts and reduction of natural vegetation and thereby the chances of the occurrence of natural fires.

which process produces large amounts of energy in a star by combining lighter elements into a heavier element

Answers

Answer:

Fusion

Explanation:

A star's energy comes from the combining of light elements into heavier elements in a process known as fusion, or "nuclear burning". It is generally believed that most of the elements in the universe heavier than helium are created, or synthesized, in stars when lighter nuclei fuse to make heavier nuclei.

Answer:

Nuclear fusion

Explanation:


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4. Give the Turkish morpheme that corresponds to each of the following translations ocean from house from hand tooth my in of our (plural marker)

Answers

Here's a breakdown of the Turkish morphemes corresponding to each of the given translations:

Ocean: The Turkish word for "ocean" is "deniz." In this case, the morpheme is "den-," which represents the root of the word.

From: The Turkish suffix for indicating direction or source is "-den/-dan." It is added to the noun preceding it to indicate movement or origin. For example, "evden" means "from the house."

House: The Turkish word for "house" is "ev." In this case, "ev" is the root morpheme.

Hand: The Turkish word for "hand" is "el." "El" is the root morpheme in this case.

Tooth: The Turkish word for "tooth" is "diş." Similarly, "diş" is the root morpheme.

My: The possessive pronoun "my" in Turkish is expressed by adding the suffix "-im" to the noun it modifies. For example, "evim" means "my house."

In: The Turkish suffix for indicating location is "-de/-da." It is added to the noun preceding it to denote a specific location. For instance, "evde" means "in the house."

Of: The genitive case in Turkish is represented by the suffix "-ın/-in/-ün/-un." It is used to show possession or association. For example, "evin" means "of the house."

Our (plural marker): The plural possessive suffix in Turkish is "-imiz/-ımız/-umuz/-ümüz." It is added to the noun preceding it to indicate possession by multiple people. For instance, "evlerimiz" means "our houses."

These are the Turkish morphemes corresponding to the given translations. It's important to note that Turkish is an agglutinative language, where morphemes are added to a root word to express various grammatical features.

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the angler fish dangles a lure like appendage to attract prey, an advantage of this strategy is:

Answers

The angler fish's ability to dangle a lure-like appendage in front of its mouth is an ingenious adaptation that gives it several advantages.

For one, this strategy allows the fish to attract prey that it would otherwise be unable to catch, giving it a wider range of potential food sources. Additionally, the lure is often brightly colored and moves in a way that is appealing to many species of fish, making it highly effective at luring in unsuspecting prey.
Another advantage of the angler fish's appendage is that it allows the fish to conserve energy. Rather than actively searching for food, the angler fish can simply wait for prey to come to it. This is particularly useful in the deep, dark depths of the ocean where food can be scarce and energy conservation is critical.
Finally, the angler fish's appendage is a highly specialized tool that has evolved over millions of years to suit the fish's needs perfectly. This level of adaptation is rare in the animal kingdom and is a testament to the incredible diversity and ingenuity of nature.

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what overlapping features of newly constructed genetic maps and physical maps enable them to more easily be correlated with one another?

Answers

Common molecular markers, high-density mapping technologies, and reference genome sequences facilitate the integration of genetic and physical mapping data for the comprehensive understanding of genome structure and function.

Genetic maps and physical maps are two complementary approaches used in genome mapping. Genetic maps use recombination frequency as a measure of distance between genetic markers, while physical maps use physical distances, usually in base pairs, to locate markers along the chromosomes. While they differ in the methods used to generate them, there are overlapping features that allow for easier correlation between the two types of maps.

Firstly, both types of maps use common molecular markers, such as single nucleotide polymorphisms (SNPs) or microsatellites, to map the genome. These markers can be used to create a genetic map and to anchor physical markers on a physical map.

Secondly, the development of high-density SNP genotyping platforms and next-generation sequencing technologies has made it possible to generate both high-density genetic maps and physical maps. This allows for more precise mapping and the ability to compare and integrate the two types of maps.

Thirdly, the availability of reference genome sequences provides a common framework for both types of maps, making it easier to align them with one another.

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what is the main focus of the human genome project?

Answers

The Human Genome Project aims to decipher the entire human genome and identify all 50,000-100,000 genes.

The Human Genome Project (HGP) was an international scientific research initiative aimed at discovering the base pairs that make up human DNA, as well as identifying, mapping, and sequencing all of the human genome's genes from both a physical and functional aspect. It began in 1990 and was finished in 2003.

It is still the greatest collaborative biological effort in the world.  Preparation for the project began after it was authorized by the US government in 1984, and it was officially launched in 1990. On April 14, 2003, it was declared complete, with approximately 92% of the genome contained.

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define adaptation and biotic and abiotic factors​

Answers

Answer:

Adaptations. Organisms have specific structures, functions, and behaviors that enable them to survive the biotic and abiotic conditions of the particular ecosystem in which they live. Organisms possess adaptations to both biotic and abiotic factors in their ecosystem that increase their chance of survival.

Explanation:

Which line (Red without enzyme or Blue with
enzyme) has a higher activation energy?


Which line (Red without enzyme or Blue with
enzyme) has a lower activation energy?
Reaction

Which line (Red without enzyme or Blue withenzyme) has a higher activation energy?Which line (Red without

Answers

Red for the first one and blue for the second one

The graph above gives the land surface air temperatures and the sea surface water temperatures from 1950 to 2016. Global
warming encompasses the changes in climate and temperature around the globe from the oceans to on land. However, when
studying the warming of Earthy's land and water temperatures, a difference between the two can be observed. From the graph, it
can be seen along most of the graph that the water temperature of the sea's surface remained lower than that of the land's surface
air temperature. What unique characteristic of water allows for this phenomenon to occur?

a. water’s heat of fusion
b. water’s conductivity of heat
c. water’s heat of vaporization
d. water’s specific heat capacity

The graph above gives the land surface air temperatures and the sea surface water temperatures from 1950

Answers

Answer:

D

Explanation:

Waters specific heat capacity

Which of the following characteristics of living things best explains why some North American birds fly south for the winter? a. Living things respond to their environment. b. Living things maintain internal balance. c. Living things are made up of units called cells. d. Living things are based on a universal genetic code.

Answers

The following characteristics of living things which best explains why some North American birds fly south for the winter is living things respond to their environment and is denoted as option A.

What is Irritability?

This is referred to as the excitatory ability that living organisms have to respond to changes in their environment.

In this scenario, the winter condition is characterized by a very low temperature which may cause freezing of the organisms and a low availability of food supply in the region which is why they  fly south to be more in a conducive environment hence option A was chosen as the correct choice.

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The characteristics of living things that best explains why some North American birds fly south for the winter is as follows: Living things respond to their environment (option A).

What are living things?

Living things are organisms that possess life in them. This means that living things possess certain characteristics that distinguish them.

The characteristics of living things are as follows:

Living things are made up of a cell or cells.They obtain and use energy to survive.A unique ability to reproduceTheir ability to growTheir ability to metabolizeTheir ability to respond to stimuliTheir ability to adapt to the environmentTheir ability to moveTheir ability to respire

According to this question, North American birds fly south for the winter because they can respond to stimuli in their environment causing them to migrate.

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What would the chromosome to the right be called after DNA replication?

Answers

Answer:​ Chromatid

Explanation:

Answer: Chromatid

Explanation: A chromatid is one of the two identical halves of a chromosome that has occurred after being replicated in order to assist with preparation for cell division.

a hormone that controls a person’s appetite might bind to hormone ________ proteins on membranes in the brain.

Answers

A hormone that controls a person's appetite is called leptin. Leptin binds to its specific receptor, which is a type of hormone receptor protein, located on the membranes of certain cells in the brain.

These cells are mainly found in the hypothalamus, which is the part of the brain that controls hunger, thirst, body temperature, and other vital functions. Leptin works by signaling the brain to reduce food intake and increase energy expenditure, thereby regulating body weight and preventing obesity.
Leptin receptors are also found in other tissues throughout the body, such as the liver, muscles, and adipose tissue. When leptin levels are low, due to a lack of food intake or a genetic mutation, the brain interprets this as a signal of starvation and triggers hunger and food-seeking behavior. On the other hand, when leptin levels are high, due to overeating or excess fat storage, the brain reduces appetite and increases metabolism to burn off excess calories.
Therefore, the binding of leptin to its receptor proteins on the membranes in the brain plays a crucial role in regulating appetite and body weight. Understanding the molecular mechanisms underlying this process is important for developing new treatments for obesity and related metabolic disorders.A hormone that controls a person's appetite is called leptin. Leptin binds to its specific receptor, which is a type of hormone receptor protein, located on the membranes of certain cells in the brain.

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the number of individuals in a population of a species that an environment can sustain log-term is known as the group of answer choices carrying capacity population dynamic sustainable population food web trophic level

Answers

The number of individuals in a population of a species that an environment can sustain log-term is known as A. Carrying capacity

It is influenced by both biotic and abiotic factors like availability of food, water, habitat, disease, predation, and competition. The carrying capacity can be exceeded by a population for a short time, but eventually, there will be a decrease in the population size, this could be due to factors like lack of food, increase in disease, or increase in predators. The population dynamics is the study of changes in population size, density, distribution, and age structure. It helps scientists understand the factors that influence the growth, decline, or stability of populations over time.

Sustainable population refers to a population size that can be maintained indefinitely without causing significant negative impacts on the ecosystem or other species, it is essential to ensure that the ecosystem remains healthy and resilient and can continue to provide ecosystem services like air and water purification, nutrient cycling, and pollination. The food web is a diagram that shows the feeding relationships between different organisms in an ecosystem. It shows how energy and nutrients are transferred from one organism to another. So therefore the correct answer is A. carrying capacity refers to the maximum number of individuals in a population of a particular species that an ecosystem can support in the long term.

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if a parent has blue eyes (bb) and. the other parent has brown eyes (Bb) what is the chance the offspring will have brown eyes? ​

Answers

Answer:

50%

Explanation: punnet square

if a parent has blue eyes (bb) and. the other parent has brown eyes (Bb) what is the chance the offspring

Which statement best describes an environmental consequence of unsealed landfills?

A. Materials in landfills undergo decomposition for hundreds of years.

B. Heavy metals are released as leachate into surrounding waterways.

C. Long-term exposure to mercury and lead in landfills can cause cancers.

D. Landfills can produce carbon dioxide that leak into the atmosphere.

Answers

Landfills can produce CO2 that leaks into the atmosphere.

The contaminants in landfill leachate build up and have a negative impact on the ecology and food chains, which may cause genotoxicity, acute toxicity, and cancer in humans.

What about landfills?A method of rubbish disposal where waste is buried under layers of soil to raise low-lying terrain.Solid waste is disposed of in well-managed, well-engineered landfills nowadays.So as to assure compliance with federal rules, landfills are strategically placed, planned, managed, and monitored.Additionally, they're made to safeguard the environment against toxins that might be found in the waste stream.While "whole filled with rubbish" might be your first impression when you hear the phrase, landfills are frequently just a way of stabilizing the ground for construction.Garbage dumps are sometimes mentioned as landfills, even when they are not physical pits that are filled and covered.A big pollutant source with a host of unfavorable consequences.In landfills, trash decomposes very slowly and poses an issue for future generations.Toxins, leachate, and greenhouse emissions from landfills are the three primary issues.Landfills may emit offensive odors, and waste gas may seep through the bottom and gather in surrounding structures.Ammonia, sulfides, methane, and CO2 are the landfill gasses that cause the most worry.The majority of landfill smells are caused by ammonia and hydrogen sulfide.

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In celiac disease, the body's immune system destroys which structure?

A. villi

B. gluten

C. cartilage

D. synovium

Answers

A. Vili in stomach. And this is because of gluten.

Answer:

Vili

Explanation:

Given the following parent below: determine the probability of each offspring.
Parent 1: IA IB DD
Parent: IAIA Dd
Blood type (ABO)

Answers

The probabilities of the offspring's blood types are 25% for blood type A, 25% for blood type AB, and 50% for blood type O.

What is ABO blood grouping?

ABO blood grouping is a system used to classify human blood into different groups based on the presence or absence of antigens on the surface of red blood cells. There are four main blood types: A, B, AB, and O. The A and B antigens are glycoproteins that are present on the surface of red blood cells, while the O antigen is the absence of both A and B antigens.

To determine the probability of each offspring's blood type, we need to first understand the inheritance patterns of the ABO blood group system. The presence or absence of two antigens, A and B, on the surface of red blood cells determines the ABO blood group system.  The possible blood types are A, B, AB, and O. The inheritance of ABO blood types follows a codominant pattern, where both alleles are expressed equally.

Each person has two copies of the ABO gene, one inherited from each parent. Three alleles are conceivable: A, B, and O. O is recessive, while A and B are codominant. The IA allele codes for the A antigen, IB allele codes for the B antigen, and the i allele (recessive) does not produce either A or B antigens.

With that said, let's look at the parent's genotypes:

Parent 1: IA IB DD

Parent 2: IAIA Dd.

The possible offspring blood types and their probabilities are:

IAIA (25%): blood type A (homozygous for the A allele)

IAi  (25%): blood type A (heterozygous for the A allele)

IAIDd (25%): blood type AB (heterozygous for both A and B alleles)

iDd  (25%): blood type O (homozygous for the i allele)

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A bacteria culture starts with 2000 bacteria. [6 marks total] a) After 6 hours the estimated count is 60 000. How long does it take for the number of bacteria to double? Round your answer to 2 decimal places of an hour. [3 marks] b) Assume the doubling period was half an hour. How long will it take the bacteria population to grow to 90000? Round your answer to 2 decimal places of an hour.

Answers

Given a bacteria culture starts with 2000 bacteria. a) It take 2.93 hours for the number of bacteria to double ; b) It will take  4.21 hours. for the bacteria population to grow to 90000.

a) After 6 hours the estimated count is 60 000. Round your answer to 2 decimal places of an hour. For calculating the time taken for a number of bacteria to double, we use the formula, t = (ln 2)/k where, t = time, k = doubling time (in hours), and ln = natural logarithm. Given that the initial number of bacteria is 2000 and the number of bacteria after 6 hours is 60 000. The estimated growth rate, k = (ln N₁  - ln N₀ )/(t₁  - t₀ ) where N₁ is the final number of bacteria, N₀ is the initial number of bacteria, t₁ is the final time, and t₀  is the initial time. So, we have k = (ln 60 000 - ln 2000)/(6 - 0) = 1.418 / 6 hours = 0.236. Therefore, t = (ln 2)/k = (ln 2)/0.236 = 2.93 hours (approximately) to double the number of bacteria. Hence, the answer is 2.93 hours.

b) Assume the doubling period was half an hour.  Round your answer to 2 decimal places of an hour. Given that the doubling period was half an hour. Therefore, the growth rate, k = 1/doubling time = 1/0.5 = 2 per hour. Let t be the number of hours to grow to 90,000 bacteria. Then, we have 90,000/2000 = 2^(t/0.5) => 45 = 2^(t/0.5) => ln 45 = (t/0.5) ln 2 => t = (ln 45)/(0.5 ln 2) = 4.21 hours (approximately). Therefore, the answer is 4.21 hours.

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Which process best describes the termination of activity of acetylcholine?
reuptake
absorption by astrocytes
enzymatic inactivation
ionic re-encapsulation

Answers

The enzymatic inactivation process best describes the termination of activity of acetylcholine.

Acetylcholine (ACh) is a neurotransmitter involved in transmitting signals across synapses in the nervous system. After ACh has carried out its function, it needs to be rapidly terminated to prevent continuous signaling. The termination of ACh activity primarily occurs through enzymatic inactivation.

The enzyme responsible for the enzymatic inactivation of ACh is called acetylcholinesterase (AChE). AChE is present in the synaptic cleft, which is the small gap between the nerve terminal (presynaptic neuron) and the target cell (postsynaptic neuron or muscle fiber). AChE quickly hydrolyzes ACh into choline and acetate.

Once ACh is hydrolyzed by AChE, the choline is taken up by the presynaptic neuron through a process called reuptake. Choline is then utilized for resynthesis of ACh. The acetate produced by the hydrolysis of ACh is released into the extracellular space and can be taken up by surrounding cells, such as astrocytes, for further metabolism.

The termination of acetylcholine activity is primarily achieved through enzymatic inactivation by acetylcholinesterase. This enzymatic process rapidly hydrolyzes acetylcholine into choline and acetate. Choline is reuptaken by the presynaptic neuron for the resynthesis of acetylcholine, while acetate can be absorbed by adjacent cells like astrocytes for further metabolic processes. This mechanism ensures the precise control and regulation of acetylcholine signaling, allowing for proper neuronal communication and preventing continuous stimulation.

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Will give brainly!!
what are some groups that influence people's perspective?​

Answers

Answer:

ther economic status influence how we perceive the place where we live and other parts of the world.

Explanation:

The farther away from the equator you are the _________ energy is transferred from the sun to the ocean surface. fill in the blank
A. More
B. Less
C. No Energy

Answers

Answer:

B

Explanation:

Less because the energy through the sun and also to the ocean surface

Answer:

B.less

Explanation:

The further a location is from the equator, the less sunlight that location receives to heat the atmosphere and thus, the temperature is colder. The reason that higher latitudes receive less sunlight is due to the shape of Earth.

I need help sooo much. I really appreciate it

I need help sooo much. I really appreciate it

Answers

Answer:

D

is the answer because as you see the percentage increase

Answer:

900

\

Explanation:

Which one of the following best describes the way in which a restriction enzyme (more properly called a restriction endonuclease) cuts DNA? O It begins cutting a DNA strand at its 5'end. O It cuts a DNA double helix at random locations along its length. O It cuts a DNA double helix at specific sequences of nucleotides. O It breaks the hydrogen bonds between the two strands of a DNA double helix, making single-stranded DNA.
Restriction enzymes such as EcoRI, BamHI, and HinDill are naturally found in: O viruses. O cancerous cells. O eukaryotic cells, such as yeasts. O bacteria.

Answers

Restriction enzymes, also known as restriction endonucleases, are enzymes found in bacteria that cleave DNA at specific sequences of nucleotides, resulting in a break in both strands of the DNA double helix.

A restriction enzyme, also known as a restriction endonuclease, is an enzyme that plays a critical role in the biology of bacteria and viruses. These enzymes are responsible for cutting DNA at specific sequences of nucleotides, allowing bacteria and viruses to defend against invading genetic material.

The restriction enzyme begins by recognizing a specific sequence of nucleotides within a DNA molecule. This sequence, called a restriction site, is typically 4-8 base pairs long and occurs several times within the genome of a bacterium or virus.

Once the restriction enzyme recognizes a restriction site, it cleaves the DNA molecule, cutting the two strands of the double helix at specific positions.

The way in which a restriction enzyme cuts DNA is by cleaving the bonds between the nitrogenous bases of the nucleotides. This cleavage results in a break in both strands of the DNA double helix, producing a series of fragments that can be separated and studied.

Restriction enzymes are naturally found in bacteria, where they play a critical role in protecting the bacterium from invading genetic material, such as bacteriophages.

Bacteria have evolved the ability to produce these enzymes as a defense mechanism against the introduction of foreign DNA. However, restriction enzymes are not found in viruses or eukaryotic cells, such as yeasts, or cancerous cells.

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Match the key choices with the appropriate description​

Match the key choices with the appropriate description

Answers

Answer:

I don't know, thanks for the point

Plants living in regions where water supplies in the soil are low develop various adaptations to aid in their survival. Suggest FOUR of these adaptations.

Answers

Plants living in regions with limited water availability have evolved various adaptations to cope with the challenging conditions.

Four common adaptations seen in such plants:

1)Succulence: Many plants in arid regions have evolved succulent structures to store water.

These plants typically have fleshy leaves, stems, or roots that can store significant amounts of water during periods of rainfall.

The stored water can then be utilized during times of drought, allowing the plant to survive extended periods without rainfall.

2)Reduced leaves or spines: To minimize water loss through transpiration, plants in arid environments often have reduced leaves or modified leaf structures.

For example, some plants have small, needle-like leaves or spines that help reduce the surface area exposed to the hot and dry air, thereby reducing water loss.

3)Deep root systems: Plants adapted to arid conditions often possess deep root systems that enable them to access water from deeper soil layers.

These extensive root systems can tap into groundwater sources or reach areas with higher moisture content, allowing the plant to survive when surface water is scarce.

4)CAM photosynthesis: Crassulacean acid metabolism (CAM) is a specialized form of photosynthesis that many arid-adapted plants employ.

CAM plants open their stomata and take in carbon dioxide during the night when temperatures are cooler and water loss through transpiration is reduced.

They store the carbon dioxide as an organic acid and utilize it during the day for photosynthesis when the stomata remain closed to conserve water.

These adaptations enable plants to conserve and efficiently utilize water, enhancing their chances of survival in regions with low water supplies.

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The production of carbon dioxide during the burning of a fuel is an example of a(n) reaction.​

Answers

Answer:

Combustion

When a fuel [organic compound containing carbon and hydrogen ] is burned in the air, the products would be water and carbon dioxide.

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